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Neurodegeneration with brain iron accumulation
Annals of Indian Academy of Neurology, 2019 The term NBIA encompasses a heterogeneous group of inherited disorders characterized clinically by progressive extra pyramidal syndrome and pathologically by excessive iron deposition in brain, primarily affecting the basal ganglia (globus pallidus ...
Amit Batla, Chandana Gaddipati
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Correlation between iron accumulation and sarcopenia in middle-aged and elderly populations [PDF]
BMC Musculoskeletal DisordersPurpose The goal of this study was to investigate the relationship between iron accumulation and sarcopenia risk. Method We conducted a cross-sectional study based on data acquired during the year 2022–2023 from the affiliated hospital of Jiangsu ...
Mahamane Rahoufou Tounaoua +3 more
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Early pathological changes in the liver and kidney of non-obese diabetic (NOD) mice: involvement of iron accumulation and ferroptosis [PDF]
Frontiers in EndocrinologyDisorders of iron metabolism and ferroptosis play an important role in the development of diabetes and related pathologies. The involvement of ferroptosis in type 1 diabetes has mainly been investigated in animal models with chemically induced diabetes ...
Ana Stancic +8 more
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Neurodegeneration with brain iron accumulation [PDF]
Arquivos de Neuro-Psiquiatria, 2016 João Carlos Papaterra Limongi
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Neurodegeneration with brain iron accumulation
Анналы клинической и экспериментальной неврологии, 2017 Neurodegeneration with brain iron accumulation (NBIA) is aclinically and genetically heterogeneous group of hereditary (predominantlyautosomal recessive) progressive disorders of the CNSwith a common feature of iron accumulation in basal ganglia ...
G. E. Rudenskaya, E. Yu. Zakharova
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Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration
Neural Regeneration Research, 2023 Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García +10 more
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Antioxidants, 2022 Aconitase 1 (ACO1) links oxidative stress and iron accumulation in Parkinson’s disease (PD). ACO1 loses its aconitase activity and turns into iron regulatory protein 1 (IRP1) upon oxidative stress.
Run-Zhe Liu +4 more
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Sirtuin 2 Alleviates Chronic Neuropathic Pain by Suppressing Ferroptosis in Rats
Frontiers in Pharmacology, 2022 Neuropathic pain (NP) is chronic and associated with poor effects of general analgesia. It affects patients’ health and quality of life. The apoptotic process of lipid peroxidation caused by iron overload is called ferroptosis, which may be associated ...
Xiaojiao Zhang +8 more
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Accumulation of iron by yersiniae [PDF]
Journal of Bacteriology, 1979 Escherichia coli, Bacillus megaterium, and three species of yersiniae grew rapidly without significant production of soluble siderophores in a defined iron-sufficient medium (20 microM Fe3+). In iron-deficient medium (0.1 to 0.3 microM Fe3+) all organisms showed reduced growth, and there was extensive production of siderophores by E.
R D, Perry, R R, Brubaker
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Role of Lipocalin-2 in Amyloid-Beta Oligomer-Induced Mouse Model of Alzheimer’s Disease
Antioxidants, 2021 Lipocalin-2 (LCN2) is an inflammatory protein with diverse functions in the brain. Although many studies have investigated the mechanism of LCN2 in brain injuries, the effect of LCN2 on amyloid-toxicity-related memory deficits in a mouse model of ...
Heeyoung Kang +13 more
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