Results 31 to 40 of about 214,451 (303)

Safety Aspects of Iron in Food [PDF]

, 2001
During the last decades efforts regarding dietary iron supply focused mostly on the prevention of deficiencies, especially during growth and pregnancy.
Schümann, Klaus
core   +1 more source

The Effects of Treadmill Exercise on Iron Accumulation and Microglia Activation in the Brain of APP-C105 Transgenic Mice of Alzheimer’s Disease [PDF]

운동과학, 2019
PURPOSE This study is to investigate the effects of treadmill exercise on iron accumulation and microglial cell activity in the cerebral cortex of APP-C105 transgenic Alzheimer’s mice. METHODS The transgenic mice and their comparative non-transgenic mice
Joo-Young Lee, Dong-Hun Choi, Hyun-Suob Um, Tae-Kyung Kim, Nam Hee Lee, Dong-Chul Yeom, Joon-Yong Cho   +6 more
doaj   +1 more source

Case Report: Identification of a De novo C19orf12 Variant in a Patient With Mitochondrial Membrane Protein–Associated Neurodegeneration

Frontiers in Genetics, 2022
Background: Mitochondrial membrane protein–associated neurodegeneration (MPAN) mostly arises as an autosomal recessive disease and is caused by variants in the chromosome 19 open reading frame 12 (C19orf12) gene.
Yue Yang, Shijie Zhang, Wenming Yang, Wenming Yang, Taohua Wei, Wenjie Hao, Ting Cheng, Jiuxiang Wang, Wei Dong, Wei Dong, Nannan Qian   +10 more
doaj   +1 more source

THE ACCUMULATION OF IRON IN TUBERCULOUS AREAS [PDF]

Journal of Experimental Medicine, 1930
Repeated intravenous injections of dilute ferric chloride solution in tuberculous rabbits markedly retard the development of the disease as evidenced both by a prolongation in the survival time and by comparison of lesions in control and experimental animals.
openaire   +2 more sources

Genetics of Neurodegeneration with Brain Iron Accumulation [PDF]

Current Neurology and Neuroscience Reports, 2011
The condition originally called Hallervorden-Spatz syndrome is a collection of related disorders involving abnormal iron accumulation in the basal ganglia, usually manifesting with a movement disorder. To date, mutations in the following genes have been associated with neurodegeneration with brain iron accumulation (NBIA) phenotypes: PANK2, PLA2G6 ...
Allison, Gregory, Susan J, Hayflick
openaire   +2 more sources

Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide β-amyloid (1-42) [PDF]

, 2014
For decades, a link between increased levels of iron and areas of Alzheimer's disease (AD) pathology has been recognized, including AD lesions comprised of the peptide β-amyloid (Aβ).
van der Laan, Gerrit, Jenkins, C.A., Collingwood, Joanna F., Everett, James, Cespedes, E., Dobson, J., Collingwood, J.F., Dobson, Jon, Arenholz, Elke, Telling, N.D., Arenholz, E., Céspedes, Eva, Shelford, Leigh R., Exley, Chris, Exley, C., Jenkins, Catherine A., Everett, J., Shelford, L.R., Telling, Neil D.   +18 more
core   +1 more source

Calibration of myocardial T2 and T1 against iron concentration. [PDF]

, 2014
BACKGROUND: The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use.
Timothy G St. Pierre, St Pierre, TG, Firmin, DN, Forni, G, Mary N Sheppard, Fleming, A, Gualtiero Catani, He, T, Gianluca Forni, Taigang He, House, M, Sofia V de Noronha, Carpenter, JP, Black, G, Walker, J, Sheppard, MN, Kirk, P, Baksi, AJ, John C Wood, Porter, JB, John B Porter, Mike House, Walker, JM, Fucharoen, S, Wood, JC, Suthat Fucharoen, A John Baksi, Pennell, DJ, Adam Fleming, Greg Black, Anderson, LJ, Baksi, A, Dudley J Pennell, Paul Kirk, Lisa J Anderson, David N Firmin, John-Paul Carpenter, J Malcolm Walker, Gildo Matta, Michael Roughton, Roughton, M, de Noronha, SV, Matta, G, Catani, G   +43 more
core   +1 more source

Brain and liver iron accumulation in aceruloplasminemia [PDF]

Neurology, 2013
A 68-year-old woman with diabetes, anemia, and retinal degeneration developed mild cognitive impairment and subtle gait ataxia. Her parents were nonconsanguineous, and her sister had diabetes. T2*-weighted brain MRI showed symmetric hypointensity in the striatum, thalamus, red nucleus, and dentate nucleus, and on the brain surface, more prominently on ...
Koji, Fujita, Yusuke, Osaki, Masafumi, Harada, Satoshi, Kono, Hiroaki, Miyajima, Yuishin, Izumi, Ryuji, Kaji   +6 more
openaire   +2 more sources

BMP9 alleviates iron accumulation-induced osteoporosis via the USP10/FOXO1/GPX4 axis [PDF]

Journal of Advanced Research
Yanran Huang, Yafei Zhu, Xiaoji Luo
exaly   +2 more sources

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

Redox Biology, 2018
Cellular senescence is characterised by the irreversible arrest of proliferation, a pro-inflammatory secretory phenotype and evasion of programmed cell death mechanisms.
Shashank Masaldan, Sharnel A.S. Clatworthy, Cristina Gamell, Peter M. Meggyesy, Antonia-Tonia Rigopoulos, Sue Haupt, Ygal Haupt, Delphine Denoyer, Paul A. Adlard, Ashley I. Bush, Michael A. Cater   +10 more
doaj   +1 more source