Results 211 to 220 of about 9,572,367 (390)

Late‐onset neurodegenerative diseases—the role of protein insolubility [PDF]

, 2000
William G. Johnson
openalex   +1 more source

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.

Immunity, 2017
S. Krasemann, C. Madore, R. Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, L. Beckers, E. O’Loughlin, Yang Xu, Zain Fanek, David J. Greco, Scott t. Smith, G. Tweet, Zachary Humulock, Tobias Zrzavy, Patricia Conde-Sanroman, Mar Gacias, Z. Weng, Hao Chen, Emily C. Tjon, F. Mazaheri, K. Hartmann, A. Madi, J. Ulrich, M. Glatzel, A. Worthmann, J. Heeren, B. Budnik, C. Lemere, T. Ikezu, F. Heppner, V. Litvak, D. Holtzman, H. Lassmann, H. Weiner, J. Ochando, C. Haass, O. Butovsky   +37 more
semanticscholar   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

Cerebrospinal Fluid Tau Levels in Neurodegenerative Diseases with Distinct Tau-Related Pathology

, 1997
Hiroyuki Arai, Yu-ichi Morikawa, Makoto Higuchi, Toshifumi Matsui, Christopher M. Clark, Masakazu Miura, Nobuo Machida, V. M.-Y. Lee, John Q. Trojanowski, Hidetada Sasaki   +9 more
openalex   +1 more source

Controlled Magnesium Ion Delivery via Mg‐Sputtered Nerve Conduit for Enhancing Peripheral Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim, Jieun Kwon, Hyeok Kim, Sunhee Lee, Seongchan Kim, Ji‐Young Lee, Khandoker Asiqur Rahaman, Taeyeon Kim, Hyojin Lee, Myoung‐Ryul Ok, Seok Chung, Hyung‐Seop Han, Yu‐Chan Kim   +12 more
wiley   +1 more source

Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution

Communications Biology
The medial prefrontal cortex (mPFC) is important for higher cognitive functions, including working memory, decision making, and emotional control. In vivo recordings of neuronal activity in the mPFC have been achieved via invasive electrical and optical ...
Falko Fuhrmann, Felix C. Nebeling, Fabrizio Musacchio, Manuel Mittag, Stefanie Poll, Monika Müller, Eleonora Ambrad Giovannetti, Michael Maibach, Barbara Schaffran, Emily Burnside, Ivy Chi Wai Chan, Alex Simon Lagurin, Nicole Reichenbach, Sanjeev Kaushalya, Hans Fried, Stefan Linden, Gabor C. Petzold, Gaia Tavosanis, Frank Bradke, Martin Fuhrmann   +19 more
doaj   +1 more source

The Expression of α-, β-, and γ-Synucleins in Olfactory Mucosa from Patients with and without Neurodegenerative Diseases

, 1999
John E. Duda, Ujashi Shah, Steven E. Arnold, Virginia M.-Y. Lee, John Q. Trojanowski   +4 more
openalex   +1 more source

Episodic–like memory in animals: psychological criteria, neural mechanisms and the value of episodic–like tasks to investigate animal models of neurodegenerative disease [PDF]

, 2001
Richard Morris
openalex   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Mitochondrial dysfunction in neurodegenerative diseases

, 1998
M. Flint Beal
openalex   +1 more source