Results 1 to 10 of about 148,627 (233)
Children, 2022 Children with Autism Spectrum Disorder (ASD) face several challenges due to deficits in social function and communication along with restricted patterns of behaviors. Often, they also have difficult-to-manage and disruptive behaviors.
Stefano Pallanti +4 more
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Frontiers in Endocrinology, 2023 Maternal health during gestational period is undoubtedly critical in shaping optimal fetal development and future health of the offspring. Gestational diabetes mellitus is a metabolic disorder occurring in pregnancy with an alarming increasing incidence ...
Kalliopi Rodolaki +5 more
semanticscholar +1 more source
Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment
Nature, 2023 The assembly of cortical circuits involves the generation and migration of interneurons from the ventral to the dorsal forebrain^ 1 – 3 , which has been challenging to study at inaccessible stages of late gestation and early postnatal human development ...
Xiangling Meng +11 more
semanticscholar +1 more source
Priority setting for children and young people with chronic conditions and disabilities
Health Expectations, 2023 Background The aim of this project was to identify the top 10 priorities for childhood chronic conditions and disability (CCD) research from the perspectives of children and young people with lived experience, their parents and caregivers and the ...
Amy Finlay‐Jones +13 more
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Genome Biology, 2021 N6-methyladenosine (m6A) modification is known to impact many aspects of RNA metabolism, including mRNA stability and translation, and is highly prevalent in the brain.
A. Shafik +12 more
semanticscholar +1 more source
Environmental Health Perspectives, 2023 Background: Widespread insecticide exposure might be a risk factor for neurodevelopment of our children, but few studies examined the mixture effect of maternal coexposure to organophosphate insecticides (OPPs), pyrethroids (PYRs), and neonicotinoid ...
Aizhen Wang +6 more
semanticscholar +1 more source
Potential Epigenetic Effects of Human Milk on Infants’ Neurodevelopment
Nutrients, 2023 The advantages of human milk feeding, especially in preterm babies, are well recognized. Infants’ feeding with breast milk lowers the likelihood of developing a diverse range of non-communicable diseases later in life and it is also associated with ...
Giannoula Gialeli +3 more
semanticscholar +1 more source
BMC Pregnancy and Childbirth, 2021 Background The post-partum period is a vulnerable time for mothers in terms of eating disorder symptoms and is critical for the establishment of feeding patterns in infants.
Rachel F. Rodgers +3 more
doaj +1 more source
The maternal microbiome modulates fetal neurodevelopment in mice
Nature, 2020 ‘Dysbiosis’ of the maternal gut microbiome, in response to challenges such as infection 1 , altered diet 2 and stress 3 during pregnancy, has been increasingly associated with abnormalities in brain function and behaviour of the offspring 4 . However, it
H. Vuong +9 more
semanticscholar +1 more source
The role of histone modifications: from neurodevelopment to neurodiseases
Signal Transduction and Targeted Therapy, 2022 Epigenetic regulatory mechanisms, including DNA methylation, histone modification, chromatin remodeling, and microRNA expression, play critical roles in cell differentiation and organ development through spatial and temporal gene regulation. Neurogenesis
Jisu Park +3 more
semanticscholar +1 more source