Results 101 to 110 of about 98,574 (255)

Acetylcholinesterase Activity and Neurodevelopment in Boys and Girls [PDF]

, 2013
BackgroundOrganophosphate exposures can affect children's neurodevelopment, possibly due to neurotoxicity induced by acetylcholinesterase (AChE) inhibition, and may affect boys more than girls.
Jacobs, David R, Alexander, Bruce H, Suarez-Lopez, Jose R, Gunnar, Megan R, Himes, John H   +4 more
core   +1 more source

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

Autism Research, EarlyView.
ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmacy across the lifespan; thus, they may be at particularly high risk of ...
Goldie A. McQuaid, Nancy Raitano Lee, Gregory L. Wallace   +2 more
wiley   +1 more source

Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation

Autism Research, EarlyView.
ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl, Kimberly Berger, Piera M. Cirillo, Nickilou Y. Krigbaum, Victor Poon, Gayle C. Windham, Barbara A. Cohn   +6 more
wiley   +1 more source

Impaired Motor Competence in Children and Adolescents With Autism Spectrum Disorder: Evidence From a Systematic Review and Meta‐Analysis

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is frequently associated with motor difficulties that may affect daily functioning, participation in physical activity, and developmental outcomes. Although motor impairments have been widely reported in this population, comparative evidence against typically developing (TD) peers remains fragmented across ...
Nerea Blanco‐Martínez, Daniel González‐Devesa, Silvia Varela, Rocío Carballo‐Afonso, Carlos Ayán‐Pérez   +4 more
wiley   +1 more source

Placental pathology predicts infantile neurodevelopment

doctoral医学系研究科浜松医科大学Hamamatsu University School of Medicine博士（医学）The aim of present study was to investigate the association of placental pathological findings with infantile neurodevelopment during the early 40 months of life. 258 singleton infants were
ウエダ, メグミ, Ueda, Megumi, 上田, めぐみ   +2 more
core   +2 more sources

Clinical and molecular genetic analysis of a Chinese patient with Cockayne syndrome caused by ERCC8 gene synonymous variant at splicing site and exon 1 deletion

Orphanet Journal of Rare Diseases
Background Cockayne Syndrome (CS) is a rare autosomal recessive genetic disease, mainly caused by ERCC8 and ERCC6 gene defect. However, many of its molecular characteristics remain unclear.
Xiaofan Bie, Lei Liu, Lingzhi Liu, Zhenkun Zhang, Mingwei Guo, Zhenhua Xie, Yaodong Zhang, Jun Su, Dongxiao Li   +8 more
doaj   +1 more source

Quality of Life in Autism: A Systematic Review and Meta‐Analysis of Patients and Caregivers

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition associated with significant challenges in daily functioning and well‐being. Caregivers often experience substantial psychological and physical burden. However, comprehensive synthesis of quality of life (QoL) outcomes for both individuals with ASD and their caregivers ...
Kamila Castro, Camila Kümmel Duarte, Eduarda Silva, Laura Hoffmann, Jenifer Lopes Borchardt, Laura Pohl, Josiane Luçardo, Myrella Lapschies, Andreia Morales Cascaes, Ana Amélia Freitas‐Vilela, Adriane Cenci, Juliana S. Vaz   +11 more
wiley   +1 more source

Long‐Term Risk of Rheumatoid Arthritis in Individuals With Autism Spectrum Disorder: A Population‐Based Matched Cohort Study

Autism Research, EarlyView.
ABSTRACT To investigate the long‐term risk of rheumatoid arthritis (RA) among individuals with autism spectrum disorder (ASD), addressing potential immune comorbidity in ASD populations. A population‐based matched cohort was assembled using Swedish registers, including 46,164 individuals diagnosed with ASD between 1987 and 2017, matched to 4,634,895 ...
Evora Hailin Zhu, Stephen Z. Levine, Matilda Morin, Weiyao Yin, Benjamin Christofferson, Johan Askling, Natalia Rivera, Abraham Reichenberg, Joseph D. Buxbaum, Sven Sandin, Benjamin Hon Kei Yip   +10 more
wiley   +1 more source

Predictors of Change in Severity of Self‐Injurious Behaviors in Preschool‐Aged Autistic Children

Autism Research, EarlyView.
ABSTRACT Self‐injurious behaviors (SIBs) affect up to 50% of autistic individuals and significantly impact quality of life and everyday functioning. Cross‐sectional studies link the presence of SIB to lower IQ, altered sensory responsivity, and poor emotion regulation, yet their effect on changes in SIB severity from early childhood to school age in ...
Joseph Boyle, Andrew Dakopolos, Olivia Surgent, Joshua K. Lee, Derek S. Andrews, Brianna Heath, Jason Smucny, Marjorie Solomon, Sally J. Rogers, Christine Wu Nordahl   +9 more
wiley   +1 more source

Effects of Cannabidiol‐Rich Cannabis Oil on Facial Expression Recognition and Theory of Mind in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

Autism Research, EarlyView.
ABSTRACT To evaluate, in a post hoc subanalysis, the effects of cannabidiol (CBD)‐rich cannabis oil on facial expression recognition and theory of mind in children with autism spectrum disorder (ASD). This post hoc subanalysis included children from a double‐blind, randomized, placebo‐controlled trial who completed social cognition assessments at ...
Wandersonia Moreira Brito Medeiros, Estácio Amaro da Silva Junior, Katy Lísias Gondim Dias de Albuquerque, Marine Diniz da Rosa, Amanda Gleiciane de Lima Oliveira, Maycon Jônatas da Silva, João Vitor Andrade Fernandes, Emily Caroline Costa Vieira, João Paulo Mendes dos Santos, Thais Cavalcanti Borges, Ana Hermínia Andrade e Silva, Carlos Espínola Neto Segundo, Nelson Torro‐Alves   +12 more
wiley   +1 more source