Results 81 to 90 of about 114,486 (309)

A Scaffold for Neurodevelopment

, 2011
DISC1, a susceptibility gene for neuropsychiatric disorders, interacts with various partners to influence distinct aspects of neurodevelopment.
Elizabeth M. Adler
core   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Huntington’s disease alters human neurodevelopment

Science, 2020
Neural progenitors disrupted Symptoms of Huntington's disease (HD) manifest in adulthood despite the aberrant protein being present much earlier in persons carrying the disease-causing mutation. Barnat et al.
M. Barnat, M. Capizzi, Esther Aparicio, Susana Boluda, Doris Wennagel, Radhia Kacher, Rayane Kassem, Sophie Lenoir, F. Agasse, B. Y. Braz, Jeh-Ping Liu, J. Ighil, A. Tessier, S. Zeitlin, C. Duyckaerts, M. Dommergues, A. Durr, S. Humbert   +17 more
semanticscholar   +1 more source

Bacteroidota and Lachnospiraceae integration into the gut microbiome at key time points in early life are linked to infant neurodevelopment

Gut microbes, 2021
The early life microbiome plays critical roles in host development, shaping long-term outcomes including brain functioning. It is not known which initial infant colonizers elicit optimal neurodevelopment; thus, this study investigated the association ...
Kaitlyn Oliphant, Mehneez Ali, M. D'Souza, Patrick D. Hughes, Dinanath Sulakhe, Annie Z. Wang, Bingqing Xie, Rummanu Yeasin, M. Msall, B. Andrews, E. Claud   +10 more
semanticscholar   +1 more source

An Injectable Electroactive Hydrogel Engineered for Stable Bioelectronic Interfaces

Advanced Materials Interfaces, EarlyView.
Injectable electroconductive hydrogels enable soft, conformal, and stable bioelectronic interfaces for electroceutical therapies. A catechol‐modified hyaluronic acid/alginate/edge‐functionalized graphene platform combines wet adhesion, shear‐thinning injectability, tissue‐matched mechanics, and electrochemical functionality.
Ying Zhou, Peng Zheng, Beverley Cheung, Chien Yu Huang, Greg Ryder, Jonathan R Clark, D S Abdullah Al Maruf, Yi‐Hui Wu, Ming‐Dou Ker, Xufeng Huang, Gordon G Wallace, Xiao Liu   +11 more
wiley   +1 more source

‘We need to make “shit” sexy’ a qualitative study exploring treatment adherence in adolescents with inflammatory bowel disease

Health Psychology and Behavioral Medicine
Background: Adolescents with inflammatory bowel disease (IBD) are faced with the complexities of acquiring self-management behaviours at a time when they are also navigating developmental challenges associated with adolescence. To date, limited treatment
Cassandra Screti, Lou Atkinson, Rachel Shaw, Rafeeq Muhammed, Gemma Heath   +4 more
doaj   +1 more source

A Systematic Review of Omega-3 Fatty Acid Consumption and Cognitive Outcomes in Neurodevelopment

American Journal of Lifestyle Medicine, 2022
Introduction: This systematic review addresses the effects of n-3 long-chain polyunsaturated fatty acids consumption on human neurodevelopment. It evaluates articles published between 2000 and 2022 investigating the cognitive outcomes during the period ...
Dean Sherzai, R. Moness, Sophia Sherzai, A. Sherzai   +3 more
semanticscholar   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Reliably quantifying the severity of social symptoms in children with autism using ASDSpeech

Translational Psychiatry
Several studies have demonstrated that the severity of social communication problems, a core symptom of Autism Spectrum Disorder (ASD), is correlated with specific speech characteristics of ASD individuals.
Marina Eni, Yaniv Zigel, Michal Ilan, Analya Michaelovski, Hava M. Golan, Gal Meiri, Idan Menashe, Ilan Dinstein   +7 more
doaj   +1 more source

Association of Cannabis Use During Adolescence With Neurodevelopment

JAMA psychiatry, 2021
Key Points Question To what extent is cannabis use associated with magnetic resonance imaging–measured cerebral cortical thickness development during adolescence?
Matthew D. Albaugh, Jonatan Ottino-González, A. Sidwell, C. Lepage, A. Juliano, M. Owens, B. Chaarani, P. Spechler, Nicholas R. Fontaine, Pierre Rioux, Lindsay B. Lewis, Seun Jeon, A. Evans, D. D’Souza, Rajiv Radhakrishnan, T. Banaschewski, A. Bokde, E. Quinlan, P. Conrod, S. Desrivières, H. Flor, A. Grigis, P. Gowland, A. Heinz, B. Ittermann, J. Martinot, M. Paillère Martinot, F. Nees, D. Papadopoulos Orfanos, T. Paus, L. Poustka, Sabina Millenet, J. Fröhner, M. Smolka, H. Walter, R. Whelan, G. Schumann, A. Potter, H. Garavan   +38 more
semanticscholar   +1 more source