Results 61 to 70 of about 114,486 (309)

The association between impaired fetal growth and neurodevelopment in childhood

, 2015
Impaired fetal growth is associated with an increased risk of negative neurodevelopmental outcomes. The majority of research to date, however, has relied on birth weight as an index of fetal growth impairment.
Murray, Elizabeth, Michelle Fernandes, Alan Stein, Elizabeth Murray   +3 more
core   +1 more source

High-risk pregnancy and its relationship with the neurodevelopment and behavior of 2-year-old children [PDF]

High-risk pregnancies elevate maternal stress, impacting offspring neurodevelopment and behavior. This study, involving 112 participants, aimed to compare perceived stress, neurodevelopment, and behavior in high-risk and low-risk pregnancies. Two groups,
Mariño Narváez, Carolina, González Pérez, Raquel, Juncosa Castro, Yaima, Juncosa-Castro, Yaima, Cruz Martínez, Milagros, Puertas González, José Antonio, Peralta Ramírez, María Isabel, Romero González, Borja   +7 more
core   +1 more source

Benefits of the Global Integration Method (Método de Integração Global - MIG) in functional priorities of parents of Brazilian children and adolescents with autism spectrum disorder

BMC Pediatrics
Background Understanding the priorities of parents of children and adolescents with autism spectrum disorder (ASD) is crucial for implementing evidence-based programs. This study aims to identify the functional priorities of parents of Brazilian children
Amanda Aparecida Alves Cunha Nascimento, Deisiane Oliveira Souto, Thalita Karla Flores Cruz, Arthur Felipe Barroso de Lima, Gabriela Silva Oliveira, Vitor Geraldi Haase   +5 more
doaj   +1 more source

Physical Activity as a Key Factor in Elevated BMI Among Children with Developmental Coordination Disorder: A Cross-Sectional Analysis

Children
Background/Objectives: Developmental Coordination Disorder (DCD) affects approximately 5% of children globally and is characterized by motor difficulties that can negatively impact physical activity levels and increase the risk of obesity.
Pablo Lizoain, Diana Rodriguez-Romero, Carmen Gándara, Leyre Gambra, Apolinar Varela, Nerea Crespo-Eguilaz, Sara Magallón, Martín Martínez   +7 more
doaj   +1 more source

Comparison of three bioinformatics tools in the detection of ASD candidate variants from whole exome sequencing data

Scientific Reports, 2023
Autism spectrum disorder (ASD) is a heterogenous multifactorial neurodevelopmental condition with a significant genetic susceptibility component. Thus, identifying genetic variations associated with ASD is a complex task.
Apurba Shil, Liron Levin, Hava Golan, Gal Meiri, Analya Michaelovski, Yair Sadaka, Adi Aran, Ilan Dinstein, Idan Menashe   +8 more
doaj   +1 more source

Impact of Maternal Environment and Inflammation on Fetal Neurodevelopment

Antioxidants
During intrauterine life, external stimuli including maternal nutrition, lifestyle, socioeconomic conditions, anxiety, stress, and air pollution can significantly impact fetal development.
C. Lubrano, F. Parisi, Irene Cetin
semanticscholar   +1 more source

Maternal DHA Impact on Child Neurodevelopment

, 2021
In this special issue, we have focused on the maternal docosahexaenoic acid, 22:6n-3 (DHA), on children’s neurodevelopment [...
Duttaroy, Asim Kanti, Asim Duttaroy
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

“What’s in It for the Kid?”: An Approach for the Bedside Ethicist

Children
Background/Objectives: Advances in paediatric care have increased the survival of children with severe neurological impairment, often accompanied by complex disability, multimorbidity, and a substantial treatment burden. Determining whether interventions
Giuliana C. Antolovich, Ingrid Sutherland, Zoe McCallum, Monica S. Cooper   +3 more
doaj   +1 more source

Detection of a de novo heterozygous ANK2 variant in a child with autism spectrum disorder and epilepsy: a case report

Egyptian Journal of Medical Human Genetics, 2023
Background The pathogenesis of autism spectrum disorder (ASD) is not fully clarified. Next-generation sequencing technologies have greatly enhanced the identification of new genes associated with ASD.
Catarina Granjo Morais, Rita Quental, Lara Lourenço, Micaela Guardiano, Cármen Silva, Miguel Leão   +5 more
doaj   +1 more source