Results 91 to 100 of about 1,437,159 (301)
A Thalamocortical Perspective on Sleep Spindle Alterations in Neurodevelopmental Disorders. [PDF]
PURPOSE OF REVIEW Neurodevelopmental disorders are a group of conditions that affect the development and function of the nervous system, typically arising early in life.
Gutierrez Herrera, Carolina +1 more
core +2 more sources
Advanced Materials, EarlyView.Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
Environmental Induction of Neurodevelopmental Disorders
Bulletin of Mathematical Biology, 2016 Chemical exposures, pre- and neonatal infections, psychosocial stress, and the cross-generational cultural and epigenetic impacts of these and other toxicants become an integrated, sometimes synergistic, signal that can overwhelm essential neurodevelopmental regulation.
openaire +3 more sources
Advanced Materials, EarlyView.We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena +7 more
wiley +1 more source
Advanced Science, EarlyView.A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang +4 more
wiley +1 more source
Background/Objectives: Atypical sensory processing is increasingly recognized as a transdiagnostic dimension of neurodevelopmental disorders (NDDs), with critical implications for emotional and behavioral regulation. This study aimed to identify distinct
Maria Eugenia Martelli +3 more
core +1 more source
Pain evaluation and management in neurodevelopmental conditions
, 2021 Individuals with neurodevelopmental disorders are at higher risk for both acute and chronic pain. Further, excessive pain exposure in known to have adverse effects on neurodevelopment and neurobehavior outcomes.
Marlon L. Wong +3 more
core +1 more source
Advanced Science, EarlyView.Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li +23 more
wiley +1 more source
Views of professionals about the educational needs of children with neurodevelopmental disorders [PDF]
, 2019 Background: Professionals play a key role in supporting children with special educational needs in schools. However, the views of those working with neurodevelopmental disorders are less known.
Van Herwegen, J +5 more
core +1 more source
Advanced Science, EarlyView.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source