Results 241 to 250 of about 470,350 (340)

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Ovarian Neuroendocrine Neoplasms: Challenges and Future Perspectives. [PDF]

J Clin Med
Di Vito V, Veroi G, Rizza L, Rota F, Baiocchini A, Macciomei MC, Lubrano C, La Salvia A, Lania A, Grillo LR, Migliaccio S, Rindi G, Baldelli R.   +12 more
europepmc   +1 more source

Recurrent urinary tract infections and psychological burden: mechanisms and integrative perspectives. [PDF]

Front Med (Lausanne)
Qian T, He Y, Yan R, Yu S, Chen Y, He W.
europepmc   +1 more source

Pangenomic Classification of Pituitary Neuroendocrine Tumors.

Cancer Cell, 2019
Mario B. Néou, C. Villa, Roberta Armignacco, A. Jouinot, M. Raffin-Sanson, A. Septier, F. Letourneur, Ségolène Diry, M. Diedisheim, B. Izac, C. Gaspar, K. Perlemoine, Victoria Verjus, M. Bernier, A. Boulin, J. Emile, X. Bertagna, F. Jaffrézic, D. Laloe, B. Baussart, J. Bertherat, S. Gaillard, G. Assié   +22 more
semanticscholar   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner, Franziska Eberhardt, Manuela Kofler, Andreas Eigentler, Atbin Djamshidian, Florian Krismer, Anton Hittmair, Heinz Zoller, Valentina Ellinger, Beatrice Heim, Klaus Seppi   +10 more
wiley   +1 more source

Current research hotspots and difficulties of chronic prostatitis/chronic pelvic pain syndrome: neuroendocrine mechanism. [PDF]

Ann Med
Shao B, Wu K, Fan Z, Gao X, Wan S, Xiao L, Zuo Y, Pi J, Sun P.   +8 more
europepmc   +1 more source

Tumor Organoids: Breakthroughs in Clinical Decision Making, Drug Development, and Translational Advances Beyond Conventional Models

Med Research, EarlyView.
ABSTRACT Tumor organoid models are revolutionizing cancer research by bridging the translational gap between conventional two‐dimensional cell cultures and animal models. This Editorial thoroughly explores the fundamental innovations of patient‐derived organoid technology.
Yimao Wu, Ruowei Sun, Gokhan Zengin, Shuai Ren, Meng‐Yao Li   +4 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source