Results 41 to 50 of about 369,175 (312)
The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
Frontiers in Endocrinology, 2021 Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by transsphenoidal surgery, a subset of these tumors are fast-growing, aggressive, recur, and remain a ...
Zhiyu Xi +10 more
doaj +1 more source
Frontiers in Neuroendocrinology, 2001 Tumor markers used in the diagnosis and follow-up of patients with neuroendocrine tumors are in most instances not specific for a given tumor and circulate under normal conditions in the serum, making their use as an early diagnostic tool difficult (low sensitivity).
Lamberts, S.W.J. +2 more
openaire +2 more sources
Robust data assimilation in river flow and stage estimation based on multiple imputation particle filter [PDF]
, 2019 In this paper, new method is proposed for a more robust Data Assimilation (DA) design of the river flow and stage estimation. By using the new sets of data that are derived from the incorporated Multi Imputation Particle Filter (MIPF) in the DA ...
Ismail, Zool Hilmi, Jalaludin, Nor Anija
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Case Reports in EndocrinologyAcromegaly is a rare disease that is caused by a growth hormone (GH) secreting pituitary tumor. This is a case of a 62-year-old man who presented with hypertrophic cardiomyopathy more than 25 years after surgical remission without other known etiologies ...
Ilan Remba-Shapiro +5 more
doaj +1 more source
Sex differences in body composition and association with cardiometabolic risk
Biology of Sex Differences, 2018 Background Body composition differs between men and women, with women having proportionally more fat mass and men more muscle mass. Although men and women are both susceptible to obesity, health consequences differ between the sexes.
Melanie Schorr +6 more
doaj +1 more source
Tolerant/Persister Cancer Cells and the Path to Resistance to Targeted Therapy
Cells, 2020 The capacity of cancer to adapt to treatment and evolve is a major limitation for targeted therapies. While the role of new acquired mutations is well-established, recent findings indicate that resistance can also arise from subpopulations of tolerant ...
Mirna Swayden +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Cell Death and DiseaseTemozolomide (TMZ) is a first-class clinical drug for patients with pancreatic neuroendocrine tumors (pNETs). However, the therapeutic effects of TMZ are limited because of the chemoresistance of pNET cells, which has not been fully elucidated.
Xin Lou +15 more
doaj +1 more source
The suppression of DNA repair induced by PARP-1 inhibitors rucaparib and olaparib in combination with the radiopharmaceutical 131I-MIBG in noradrenaline transporter-expressing xenograft tumors [PDF]
, 2018 No abstract ...
Gaze, Mark N. +4 more
core +1 more source