Results 131 to 140 of about 1,553,841 (335)

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types. [PDF]

, 2019
Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors.
Aran, D, Butte, AJ, Charalel, J, Chen, B, Goldstein, T, Sirota, M, van 't Veer, LJ, Wolf, DM, Yau, C, Yu, K   +9 more
core   +1 more source

Treatment challenges in and outside a specialist network setting: Pancreatic neuroendocrine tumours [PDF]

, 2019
Pancreatic Neuroendocrine Neoplasms comprise a group of rare tumours with special biology, an often indolent behaviour and particular diagnostic and therapeutic requirements.
Almar E., Arveux P., Autelitano M., Baldi I., Bara S., Barchielli A., Benfatto L., Benhamou E., Bento M. J., Bielska-Lasota M., Blaszczyk J., Bordoni A., Botta L., Bouchardy C., Bouvier A. -M., Bouvier V., Brewster D. H., Calleja N., Candela P., Caplin M., Capocaccia R., Carulla M., Clough-Gorr K., Colonna M., Comber H., De Angelis R., de Lacerda G. F., de Munain A. L., Diaz Garcia J. M., Diba C. S., Dimitrova N., Dusek L., Engel J., Ess S. M., Falcini F., Falconi M., Ferretti S., Filiberti R. A., Fusai G. K., Fusco M., Galceran J., Gatta G., Gavin A., Gennaro V., Gentilini M., Giacomin A., Gozdz S., Grosclaude P., Guizard A. -V., Hackl M., Heidrich J., Henau K., Holleczek B., Huws D. W., Iannelli A., Johannesen T. B., Jonasson J. G., Kepska K., Knijn A., Konzelmann I., Kunkler I., Lapotre-Ledoux B., Larranaga N., Leinonen M., Luttmann S., Lykoudis P. M., Madeddu A., Magi M., Malila N., Mallone S., Mangone L., Marani E., Marcos-Gragera R., Maspero S., Maynadie M., Mazzoleni G., Michiara M., Miranda A., Molinie F., Monnereau A., Moreno-Iribas C., Mousavi M., Muffatti F., Navarro C., Nennecke A., Pannozzo F., Partelli S., Pierannunzio D., Piffer S., Pildava S., Primic-Zakelj M., Rachtan J., Rashbass J., Ricci P., Robaszkiewicz M., Rossi S., Rugge M., Salmeron D., Sanchez M. J., Santaquilani M., Sardo A. S., Schubert-Fritschle G., Schvartz C., Sekerija M., Sensi F., Serraino D., Smailyte G., Spagnoli G., Stabenow R., Stracci F., Tagliabue G., Tavilla A., Torrella-Ramos A., Trama A., Tretarre B., Troussard X., Tumino R., Usala M., Van Eycken E., Velten M., Visser O., Vitale F., Woronoff A. -S., Ziino A.   +123 more
core   +1 more source

Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance High-grade neuroendocrine tumors (large-cell neuroendocrine cell carcinoma, LCNEC, and small-cell lung carcinoma, SCLC) are recalcitrant cancers for which more effective treatments and follow-up detection systems are urgently needed ...
Sara Lázaro, M. Pérez-Crespo, C. Lorz, A. Bernardini, M. Oteo, A. Enguita, E. Romero, Pilar Hernández, L. Tomás, M. Morcillo, J. Paramio, Mirentxu Santos   +11 more
semanticscholar   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source

Prostate neuroendocrine carcinoma successfully treated with etoposide and cisplatin

IJU Case Reports
Introduction The frequency of neuroendocrine carcinoma of the prostate is low, accounting for approximately 1%–5% of all prostate cancers. Herein, we report the case of a patient who was diagnosed with prostate neuroendocrine carcinoma and successfully ...
Masanori Ishizaki, Masaru Hasumi, Kazumichi Muramatsu, Nobuaki Shimizu   +3 more
doaj   +1 more source

Neuroendocrine Carcinoma of Urinary Bladder: Misdiagnosed Neoplasm

Online Journal of Health & Allied Sciences, 2020
Neuroendocrine carcinoma of the urinary bladder is an exceedingly rare pathology, comprising 0.35- 0.70% of all bladder cancers. The presenting symptoms and gross morphology are identical to conventional urothelial carcinoma, but the prognosis is much ...
Deepa Hunasghatta Chandrappa, Kanthilatha Pai   +1 more
doaj  

Surgical resection for clinical stage I high-grade neuroendocrine carcinoma of the lung

World Journal of Surgical Oncology, 2018
Background There are few reports about the factor influencing the prognosis of high-grade neuroendocrine carcinoma. In this study, we evaluated surgical outcome of clinical stage I high-grade neuroendocrine carcinoma.
Eisuke Mochizuki, Shun Matsuura, Kyohei Oishi, Koichi Miyashita, Koshiro Ichijyo, Syunya Furukawa, Miyuki Nagaoka, Shinichiro Mikura, Masaru Tsukui, Naoki Koshimizu, Shogo Sakurai, Kazuhiro Asada, Toshihiro Shirai   +12 more
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Pure large cell neuroendocrine carcinoma of the bladder without urological symptoms

The Pan African Medical Journal, 2018
Neuroendocrine carcinoma is one of the uncommonly seen pathologies of the urinary bladder. Macroscopic hematuria is frequently encountered symptom in patients with neuroendocrine carcinoma.
Ekrem Akdeniz, Mustafa Bakirtas, Mustafa Suat Bolat, Sevda Akdeniz, Ismail Özer   +4 more
doaj   +1 more source

Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. [PDF]

, 2016
The αvβ3 integrin is known to be highly upregulated during cancer progression and promotes a migratory and metastatic phenotype in many types of tumors.
Fedele, Carmine, Keen, James H., Languino, Lucia R., Lu, Huimin, Nevalainen, Marja T., Singh, Amrita   +5 more
core   +2 more sources