Results 141 to 150 of about 800,754 (297)

Circulating Tumor Cell Synaptophysin and Androgen Receptor Expression Reflect Prostate Cancer Phenotypes in Metastatic Disease

The Prostate, EarlyView.
ABSTRACT Background Chronic exposure to androgen receptor (AR)‐targeted therapies can drive lineage plasticity, leading to treatment resistance and neuroendocrine prostate cancer (NEPC), characterized by loss of AR expression and acquisition of neuroendocrine (NE) markers including synaptophysin (SYP). We evaluated concordance between circulating tumor
Ethan Lo, Alisa Clein, Michael Tam, Sara Trimble, Michael Hardin, Arturo Ramirez, Eric Kaldjian, Evan Y. Yu, Heather H. Cheng, Todd A. Yezefski, Andrew C. Hsieh, Petros Grivas, Bruce Montgomery, Peter S. Nelson, Michael T. Schweizer, Daniel E. Sabath, Steven Blinka   +16 more
wiley   +1 more source

Impact of sleep insufficiency and recovery on cancer development

Sleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan, Brian Sheng Yep Yeo, Manish Warrier, Jun He Chan, Lu Hui Png, Shuhui Xu, Kimberley LiQin Kiong, Edward C. Kuan, Tze Choong Charn, Neville Wei Yang Teo   +9 more
wiley   +1 more source

Neuroendocrine carcinoma of the nasopharynx - a case report.

, 2011
Small cell neuroendocrine carcinoma, also known as oat cell carcinoma is a frequently encountered bronchogenic neoplasm. Neuroendocrine carcinomas of the head and neck are rare aggressive tumors and pose a diagnostic and management challenge ...
Subha, Sethu Thakachy
core   +1 more source

Perioperative Outcomes of Patients With Pancreatic Neuroendocrine Neoplasms in the Context of Different Body Composition Phenotypes

World Journal of Surgery, EarlyView.
Pancreatic neuroendocrine neoplasms (pNEN) are rare and heterogeneous tumors with increasing incidence. While surgical resection remains the only curative treatment, perioperative outcomes are influenced by patient‐related risk factors. Recent research highlights body composition (BC) as a prognostic marker in oncological and transplantation surgery ...
Fabiola A. Bechtiger, Mariah Herbrich, Hazem K. A. A. Hassan, Jörg Kaiser, Thomas Hank, Magdalena Lewosinska, Deniz Uluk, Osman Öcal, Nicole D. Hildebrand, Steven WM Olde Damink, Franck Billmann, Zoltan Czigany, Mohammed Al‐Saeedi   +12 more
wiley   +1 more source

Sentinel Lymph Node Biopsy in Clinically Node‐Negative Merkel Cell Carcinoma: An Update of the Westmead Hospital Experience

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine malignancy with a high risk of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used to stage clinically node‐negative disease and to guide adjuvant therapy decisions.
Julie Ahn, Julie R. Howle, Michael J. Veness   +2 more
wiley   +1 more source

Anastomotic Failure Is Not Affected by Anastomotic Technique in Minimally Invasive Two‐Stage Oesophagectomy

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The choice of anastomotic technique in minimally invasive oesophagectomy (MIO) may influence postoperative morbidity and long‐term outcomes. The primary aim of our study is to determine whether circular (CS) or linear‐stapled (LS) anastomosis is associated with anastomotic complications following MIO.
L. Vu, C. Cabalag, L. Ng, B. Choo, A. Hardley, S. Kariyawasam   +5 more
wiley   +1 more source

Cancer Transmission in Deceased Donor Organ Transplantation: An Australian Population‐Based Linkage Study of Donor Referral Data

ANZ Journal of Surgery, EarlyView.
No cancer transmissions were observed among recipients of organs from donors with breast or prostate cancer. More than one‐quarter of potential donors forgone for common cancer risk had no verified cancer or minimal‐to‐low transmission risk, suggesting that improved risk assessment could safely increase organ donation.
Brenda Maria Rosales, Claire Johnston, James A. Hedley, Nicole De La Mata, Claire M. Vajdic, Sarah White, Patrick J. Kelly, Elena Cavazzoni, Kate Wyburn, Angela C. Webster   +9 more
wiley   +1 more source