Results 131 to 140 of about 800,754 (297)

Core Needle Biopsy in the Diagnosis of Major Salivary Gland Tumors

The Laryngoscope, EarlyView.
In this retrospective study, the diagnostic utility and reliability of CNB were evaluated in 247 CNB samples obtained from 217 patients with major salivary gland lesions, including both surgically confirmed lesions and conservatively managed cases. High diagnostic accuracy was demonstrated for CNB in the evaluation of major salivary gland lesions, and ...
Mira Naukkarinen, Jetta Kelppe, Susa Saarinen, Katri Aro, Antti Mäkitie, Jussi Tarkkanen, Timo Atula   +6 more
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Large Cell Neuroendocrine Carcinoma of the Lung

, 1995
We report three cases of neuroendocrine tumors of the lung characterized by large pleomorphic cells with frequent mitosis, which show neuroendocrine differentiation by both light microscopy or electron microscopy and immunohistochemistry.
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core  

Figure S1 from Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome

, 2018
A) Overall survival according to the original established diagnosis in patients included in the panel-consensus revision (n=232). B) Overall survival according to the panel-consensus diagnoses. Abbreviations: NSCLC NED, non-small cell lung carcinoma with
James D. McKay (3720076), Harry J.M. Groen (15001517), Noémie Leblay (15001511), Erik Thunnissen (585682), Egbert F. Smit (7507295), Ernst-Jan M. Speel (10008572), Amélie Charbrier (15001523), Lynnette Fernandez-Cuesta (15000495), Jules L. Derks (15001508), Esther C. van den Broek (15001520), Matthieu Foll (105142), Robert Jan van Suylen (15001514), Ronald Damhuis (5998103), Michael den Bakker (249874), Anne-Marie C. Dingemans (7538297)   +14 more
core   +1 more source

Network based approach identifies miR‐145‐3p as a central regulatory hub associated to the progression from localized to metastatic medullary thyroid carcinoma

The Journal of Pathology, EarlyView.
Abstract Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor originating from calcitonin producing C‐cells and accounts for 1–5% of thyroid cancers. Total thyroidectomy is curative in localized disease (N0), whereas lymph node metastases (N1) are associated with poorer prognosis.
Anna Citarella, Manuela Petti, Zein Mersini Besharat, Caterina Alfano, Elena Splendiani, Sofia Trocchianesi, Sara Cassandro, Martina Chiacchiarini, Claudia Sabato, Francesca Gianno, Tanja Milena Autilio, Martina Brunetti, Giuseppina Catanzaro, Antonella Verrienti, Rossella Elisei, Raffaele Ciampi, Cristina Romei, Maria Grazia Castagna, Silvia Cantara, Vincenzo Marotta, Luciano Pezzullo, Lorenzo Farina, Cosimo Durante, Agnese Po, Elisabetta Ferretti   +24 more
wiley   +1 more source

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma. [PDF]

Histopathology
Frequently positive TROP2 IHC suggests that TROP2 antibody‐drug conjugates may be potential treatments for LCNEC. Introduction TROP2 antibody‐drug conjugates have shown promising anti‐tumour activity, but neither the activity of these agents nor TROP2 expression has been well studied in pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare and ...
Minkley M, Ravasia K, Nghiem T, Gao D, Feng J, Churg A, Naso JR.   +6 more
europepmc   +2 more sources

Nasopharyngeal neuroendocrine carcinoma: A case report

, 2008
Neuroendocrine carcinoma is a type of neuroendocrine system neoplasm that occurs in organisms in which amine precursor uptake and decarboxylation (APUD) cells are uncommon.
Daneshi, A., Mohebbi, A.R., Emami, A.R.
core  

Spatial transcriptomics reveals club cell features and strong CLDN18 expression along the mucinous pathway to invasive mucinous adenocarcinoma

The Journal of Pathology, EarlyView.
Abstract Invasive mucinous adenocarcinoma (IMA) of the lung is a distinct subtype of lung adenocarcinoma with unique clinicopathologic features; however, its histogenesis remains incompletely understood. Although mucinous metaplasia has been suspected as a precursor lesion, direct molecular evidence supporting this progression is limited. In this study,
Joon Young Park, Do Yeon Kim, Hyun Jung Lee, Jung Hee Lee, Hae Ryoun Park, Dong Hoon Shin   +5 more
wiley   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

The Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source