Results 231 to 240 of about 800,754 (297)

Primary Hepatic Neuroendocrine Neoplasms: Systematic Review and Expert Pathologist Reappraisal Using the WHO 6th Edition Framework

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Primary hepatic neuroendocrine neoplasms (PHNENs) are exceedingly rare. Published evidence often lacks adequate clinicopathological support for a primary hepatic origin and uses inconsistent historical terminology. Previous reviews have pooled well‐differentiated neuroendocrine tumours (NETs), poorly differentiated neuroendocrine carcinomas ...
Marcello Maestri, Ottavia Cicerone, Alessandro Gambella, Federica Grillo, Stefano La Rosa, Silvia Uccella, Alessandro Vanoli   +6 more
wiley   +1 more source

Challenges in the Diagnosis of Concurrent T-Lymphoblastic Leukemia/Lymphoma and Thymic Neuroendocrine Carcinoma: A Case Report. [PDF]

Case Rep Pathol
Oliveira K, Doan M, Pei Y, Yared M, Zhang S.   +4 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, Volume 600, Issue 19, Page 2850-2873, October 2026.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC): An Aggressive Disease Course and Limitations for Personalized Oncology. [PDF]

Oncol Ther
Oanæs C, Garresori H, Lea D, Roalsø MTT, Haslerud TM, Brede C, Søreide K.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, Volume 20, Issue 10, Page 2424-2448, October 2026.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Primary Large Cell Neuroendocrine Carcinoma of the Bladder Successfully Treated With Radical Cystectomy Alone: A Case Report. [PDF]

Clin Case Rep
Aoki S, Kawahara T, Nishino Y, Tsukada H, Hirano T, Iwamoto G, Fusayasu S, Teranishi JI, Makiyama K, Hayashi H, Uemura H, Moriyama M, Ohta J.   +12 more
europepmc   +1 more source

Primary MiNEN of the urinary bladder with large cell neuroendocrine carcinoma and enteric-type adenocarcinoma: a case report. [PDF]

Front Oncol
Xiu X, Li J, Duan L, Wang X, Guo Z, Xiao X, Han Q, Gao F.   +7 more
europepmc   +1 more source

Cervical mixed small cell neuroendocrine carcinoma and adenocarcinoma with genital tract dissemination: a case report and literature review. [PDF]

Front Oncol
Liu P, Fang H, Tang X, Dong Q, Xie T, Feng J.   +5 more
europepmc   +1 more source