Results 261 to 270 of about 113,897 (352)

Homeobox B13 activates the hypoxia‐inducible factor 1 pathway through histone lactylation thereby reprogramming lipid metabolism and promoting sorafenib resistance in hepatocellular carcinoma

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Lactylation‐mediated metabolism reprogramming in HCC sorafenib resistance. In sorafenib‐resistant hepatocellular carcinoma (HCC) cells, lactate accumulation drives histone H3 lysine 18 lactylation (H3K18la). This modification is specifically enriched in the promoter region of homeobox B13 (HOXB13), activating HOXB13 transcription and upregulating its ...
Qingqing Xie   +5 more
wiley   +1 more source

Primary gastric combined adenosmall cell neuroendocrine carcinoma

open access: bronze, 2013
Tarun Rustagi   +4 more
openalex   +2 more sources

SIRT1: Protean roles at the nexus of health, disease, and therapeutics

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley   +1 more source

Fascia‐Fat‐Fascia “Sandwich Graft” Decreases Postoperative Cerebrospinal Fluid Leak Rate for High‐Flow Skull Base Defects

open access: yes
International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 646-649, June 2026.
Vidit M. Talati   +11 more
wiley   +1 more source

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

open access: yesChronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 85-99, June 2026.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves   +8 more
wiley   +1 more source

Pure large-cell neuroendocrine carcinoma of the bladder with pelvic organ invasion: A case report. [PDF]

open access: yesUrol Case Rep
Chebbi S   +5 more
europepmc   +1 more source

Supplementary Material for: Pulmonary Carcinoids and Low-Grade Gastrointestinal Neuroendocrine Tumors Show Common MicroRNA Expression Profiles, Different from Adenocarcinomas and Small Cell Carcinomas

open access: green, 2017
T. Yoshimoto   +9 more
openalex   +1 more source

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