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Imaging of Neuroendocrine Tumors
Expert Opinion on Medical Diagnostics, 2016Neuroendocrine tumors (NETs) comprise a heterogeneous group of malignancies with a very variable clinical expression and progression. They present unique properties that are important to consider for radiological and nuclear imaging, such as APUD-characteristics (amine precursor uptake and dearboxylation), as well as the expression of somatostatin ...
Kjell, Öberg, Anders, Sundin
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Neuroendocrine Tumors of the Lung
Thoracic Surgery Clinics, 2021Pulmonary neuroendocrine tumors (NETs) are relatively rare; however, their incidence is steadily increasing. They now comprise 1% to 2% of all lung cancers. Lung NETs are classified based on the World Health Organization classification into low-, intermediate-, and high-grade tumors.
Simran, Randhawa +2 more
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Pituitary, 2006
The RET proto-oncogene encodes a receptor tyrosine kinase that is a main component of the signaling pathway activated by the glial cell line-derived neurotrophic factor family ligands. Gene targeting studies revealed that signaling through RET plays a crucial role in neuronal and renal organogenesis. It is well-known that germline mutations in RET lead
Yoshiki, Murakumo +4 more
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The RET proto-oncogene encodes a receptor tyrosine kinase that is a main component of the signaling pathway activated by the glial cell line-derived neurotrophic factor family ligands. Gene targeting studies revealed that signaling through RET plays a crucial role in neuronal and renal organogenesis. It is well-known that germline mutations in RET lead
Yoshiki, Murakumo +4 more
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Pancreatic neuroendocrine tumors
Current Opinion in Gastroenterology, 2019Pancreatic neuroendocrine tumors (pNETs) are a rare, heterogeneous group of pancreatic neoplasms with a wide range of malignant potential. They may manifest as noninfiltrative, slow-growing tumors, locally invasive masses, or even swiftly metastasizing cancers.In recent years, because of the increasing amount of scientific literature available for ...
Perri G., Prakash L. R., Katz M. H. G.
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Chromogranin A and neuroendocrine tumors
Endocrinología y Nutrición (English Edition), 2013Chromogranin A (CgA) is the most abundant granin in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). As a tumor marker is moderately sensitive and nonspecific. Despite the limitations of testing methods, which require careful interpretation, especially in the case of gastrinomas, patients treated with somatostatin analogues, and poorly ...
José Ángel, Díaz Pérez +1 more
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Journal of Computer Assisted Tomography, 2014
Several classification systems for neuroendocrine tumors (NETs) exist, which use variable terminology and criteria for grading and staging. This variability in terminology can cause confusion and difficulty in recognizing which tumors are, in fact, members of this heterogeneous group of malignancies.
Melissa A, Jacobs +5 more
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Several classification systems for neuroendocrine tumors (NETs) exist, which use variable terminology and criteria for grading and staging. This variability in terminology can cause confusion and difficulty in recognizing which tumors are, in fact, members of this heterogeneous group of malignancies.
Melissa A, Jacobs +5 more
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Pulmonary Neuroendocrine Tumors
Surgical Pathology Clinics, 2020Pulmonary neuroendocrine tumors represent a morphologic spectrum of tumors from the well-differentiated typical carcinoid tumor, to the intermediate-grade atypical carcinoid tumor, to the high-grade neuroendocrine carcinomas composed of small-cell carcinoma and large-cell neuroendocrine carcinoma.
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Gastroenteropancreatic Neuroendocrine Tumors
GastroenterologyNeuroendocrine tumors (NETs) represent a heterogeneous group of neoplasms with diverse biological and clinical behavior, and gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are the most common subtype. This review provides an overview of GEP-NETs, with a focus on incidence trends, pathologic classification, diagnostic strategies, therapeutic ...
Namrata, Vijayvergia +2 more
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Neuroendocrine tumors of the lung
Current Opinion in Oncology, 2008The aim of this article is to answering different questions related to the treatment and prognosis of neuroendocrine lung tumors.In neuroendocrine lung tumors, regardless of the grade of tumoral malignancy, the general growth during the past years of the nodal involvement percentage detected in lung neuroendocrine tumors might be explained by accepting
Mariano, García-Yuste +2 more
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Pancreatic Neuroendocrine Tumors
Surgical Pathology Clinics, 2016Pancreatic neuroendocrine neoplasms include well-differentiated pancreatic neuroendocrine tumors (PanNETs) and neuroendocrine carcinomas (NECs) with well-differentiated PanNETs accounting for most cases. Other pancreatic primaries and metastatic carcinomas from other sites can mimic pancreatic neuroendocrine neoplasms.
Safia N, Salaria, Chanjuan, Shi
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