Results 31 to 40 of about 3,005,108 (342)

How to Classify Pituitary Neuroendocrine Tumors (PitNET)s in 2020

open access: yesCancers, 2020
Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors (PitNET), are mostly benign, but may present various behaviors: invasive, “aggressive” and malignant with metastases.
J. Trouillas   +5 more
semanticscholar   +1 more source

MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors

open access: yesActa Biochimica et Biophysica Sinica, 2022
Pancreatic neuroendocrine tumor (pNET) is the second most common malignant tumors of the pancreas. Multiple endocrine neoplasia 1 ( MEN1) is the most frequently mutated gene in pNETs and MEN1-encoded protein, menin, is a scaffold ...
Ye Zeng   +16 more
doaj   +1 more source

Discussing motherhood when the oncological prognosis is dire: ethical considerations for physicians

open access: yesESMO Open, 2020
Physicians are increasingly open to discussing and supporting pregnancy after cancer treatment. However, counselling patients who are seeking pregnancy despite advanced oncological disease and/or uncertain prognosis is still challenging. Two paradigmatic
Francesca Spada   +3 more
doaj   +1 more source

A Phase II Basket Trial of Dual Anti–CTLA-4 and Anti–PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Nonpancreatic Neuroendocrine Tumors

open access: yesClinical Cancer Research, 2020
Purpose: Immune checkpoint blockade has improved outcomes across tumor types; little is known about the efficacy of these agents in rare tumors. We report the results of the (nonpancreatic) neuroendocrine neoplasm cohort of SWOG S1609 dual anti–CTLA-4 ...
S. Patel   +21 more
semanticscholar   +1 more source

Biomarkers in neuroendocrine tumors

open access: yesFrontiers in Bioscience, 2010
Here, we review the role of clinical biomarkers (tissue and circulating markers) in the management of neuroendocrine tumors. These tumors may originate in different organs, from cells embriologically different but expressing common phenotypic characteristics, such as the immuno-reactivity for markers of neuro endocrine differentiation (defined as "pan ...
BERRETTA M   +7 more
openaire   +6 more sources

THE GASTROINTESTINAL NEUROENDOCRIN TUMORS

open access: yesArta Medica, 2021
Objectives. The gastrointestinal neuroendocrin tumors are rare events with clinical presentation widely variable and surgical management that is often challenging. Material and methods. We performed a retrospective study in the First Surgical Clinic, St Spiridon University Hospital, “Grigore T.
Delia Ciobanu   +8 more
openaire   +4 more sources

Blood Transcript Profiling for the Detection of Neuroendocrine Tumors: Results of a Large Independent Validation Study

open access: yesFrontiers in Endocrinology, 2018
Background: Available neuroendocrine biomarkers are considered to have insufficient accuracy to discriminate patients with gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) from healthy controls.
Mark J. C. van Treijen   +15 more
doaj   +1 more source

Multimodality imaging differentiation of pancreatic neuroendocrine tumors and solid pseudopapillary tumors with a nomogram model: A large single-center study

open access: yesFrontiers in Surgery, 2022
BackgroundPancreatic neuroendocrine tumors (pNETs) and solid pseudopapillary tumors (SPTs) are two of the most common pancreatic neoplasms with different treatment procedures.
Hai-Feng Hu   +37 more
doaj   +1 more source

NETest liquid biopsy is diagnostic of small intestine and pancreatic neuroendocrine tumors and correlates with imaging

open access: yesEndocrine Connections, 2019
Introduction: Current monoanalyte biomarkers are ineffective in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). NETest, a novel multianalyte signature, provides molecular information relevant to disease biology.
Anna Malczewska   +9 more
doaj   +1 more source

The prognostic analysis of different metastatic patterns in pancreatic neuroendocrine tumors patients

open access: yesMedicine, 2019
Objective: To evaluate the prognostic value of pancreatic neuroendocrine tumors (pNETs) with different metastatic patterns. Methods: Data of pNETs cases were extracted from the Surveillance, Epidemiology, and End Result (SEER) database.
Sumei Wang   +3 more
semanticscholar   +1 more source

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