Results 91 to 100 of about 202,243 (244)

Clinical outcome and long-term survival in 118 consecutive patients with neuroendocrine tumours of the pancreas

, 2008
BACKGROUND: The aim was to assess the clinical relevance of the World Health Organization and tumour node metastasis (TNM) classifications in patients with pancreatic neuroendocrine tumours (pNETs).
Friess, H, Kleeff, J, Esposito, I, Fischer, L, Hinz, U, Zimmermann, A, Büchler, M W   +6 more
core   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

BJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek, M. Almquist, A. O. Bergenfelz, T. J. Musholt, E. Nordenström, on behalf of the EUROCRINE® Council, M. Almquist, M. Barczynski, L. Brunaud, T. Clerici, M. H. Hansen, M. Iacobone, Ö. Makay, F. F. Palazzo, N. Muñoz‐Pérez, M. Raffaelli, P. Riss, S. van Slycke, M. R. Vriens   +18 more
wiley   +1 more source

Expression of parathyroid hormone-related protein in gastrointestinal malignancies. [PDF]

, 2006
Parathyroid hormone-related protein (PTHrP) is a peptide hormone which, when abundantly produced by certain tumours, and released into the systemic circulation, stimulates via an endocrine-like pathway, bone resorption and renal calcium reabsorption, by ...
McStay, M.K.G.
core  

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumours: Surgery for Small Intestinal and Pancreatic Neuroendocrine Tumours

, 2017
The small intestine and pancreas are among the most frequent abdominal sites of origin of neuroendocrine tumours. Distinctive features of these forms are represented by the relatively low incidence and the wide heterogeneity in biological behaviour.
Jean-Yves Scoazec, Pape, Ulrich Frank, Ruszniewski, Philippe, Ferone D, Scoazec, Jean Yves, Nieveen van Dijkum, Els J M, Nieveen van Dijkum, Els J. M., Ramage, John, Stefano Partelli, Bruno Niederle, Falconi, Massimo, Bartsch, Detlef K., Reza Kianmanesh, Nieveen Van Dijkum, Els J.M., Nick Reed, Bartsch, Detlef K, Toumpanakis, Christos, Jaume Capdevila, John Ramage, Christos Toumpanakis, Ulrich-Frank Pape, Massimo Falconi, Reed, Nick, Scoazec, Jean-Yves, Kianmanesh, Reza, Capdevila, Jaume, Niederle, Bruno, Knigge, Ulrich, Jie Chen, Andreas Pascher, Detlef K. Bartsch, Chen, Jie, Els J.M. Nieveen van Dijkum, Ulrich Knigge, null null, Partelli, Stefano, Pape, Ulrich-Frank, Philippe Ruszniewski, Pascher, Andreas   +38 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Small-Cell Neuroendocrine Carcinoma of the Cervix Masquerading as a Cervical Fibroid: Report of a rare entity

Sultan Qaboos University Medical Journal, 2018
Primary neuroendocrine tumours of the cervix are extremely rare, with an incidence of only 0.5–1%; as such, these entities can present a clinical and diagnostic challenge.
Mukta Pujani, Kanika Singh, Varsha Chauhan, Raina Chawla, Rashmi Ahuja   +4 more
doaj   +1 more source

Duodeno-pancreatic neuroendocrine tumours

European Journal of Cancer Care, 2010
Duodeno-pancreatic neuroendocrine tumours (DP-ETs) are increasingly diagnosed today due to the widespread use of modern imaging methods. Duodeno-pancreatic endocrine tumours should be treated by radical surgical resection, which offers a high chance for cure when the disease is localized.
Peros, G., Sakorafas, G.H., Konstantoudakis, G., Giannopoulos, G.A., Petropoulou, K., Parasi, A.   +5 more
openaire   +3 more sources

Small intestinal neuroendocrine tumours - Disease models, tumour development, and remedy [PDF]

, 2019
Small intestinal neuroendocrine tumours (SINETs) are malignant neoplasms which at the time of diagnosis often present with distant metastasis. The field of SINET research faces several challenges. There is a lack of preclinical models for studying SINETs,
Hofving, Tobias
core   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source