Results 1 to 10 of about 26,212 (200)

Imaging diagnosis of plexiform neurofibroma- unravelling the confounding features: A report of two cases

Radiology Case Reports, 2021
Peripheral nerve sheath tumors such as neurofibroma, comprise 5% of all benign soft tissue tumors and usually occur due to an underlying neurofibromatosis.
Dr. Shabnam Bhandari Grover, MD, DNBE, FICR, MNAMS, MRCR, FICMU, Dr. Rohit Kundra, MBBS, Dr. Hemal Grover, MBBS, MD, Dr. Vishal Gupta, MBBS, MD, Dr. Rishab Gupta, MBBS   +4 more
doaj   +2 more sources

Exuberant Plexiform Neurofibroma

Acta Médica Portuguesa, 2023
N/a.
Catarina Correia, Miguel Reis, Paulo Filipe   +2 more
doaj   +3 more sources

A special neurofibroma, plexiform neurofibroma [PDF]

ACTUALIDAD MEDICA, 2021
I. Pérez-López, J.D. Herrera-García
openaire   +2 more sources

Oral plexiform neurofibroma

Journal of Dental Sciences, 2016
Yu-Hsueh Wu
doaj   +3 more sources

Plexiform neurofibroma

Cleveland Clinic Journal of Medicine, 2016
Plexiform neurofibromas represent an uncommon variant (30%) of neurofibromatosis type 1 (NF-1) in which neurofibromas arise from multiple nerves as bulging and deforming masses involving also connective tissue and skin folds.We report a rare case of a 30-year-old man who presented with a progressive facial deformity that began in early childhood.
Tchernev, Georgi, Chokoeva, Anastasiya Atanasova, Patterson, James W., Bakardzhiev, Ilko, Wollina, Uwe, Tana, Claudio   +5 more
  +7 more sources

A case report of a 4-year-old girl with neurofibromatosis type 1

Cancer Treatment and Research Communications, 2022
Neurofibromatosis type 1 is a rare genetic disorder, which is a benign nerve tumor resulting from aberrant growth of the cells of nerve sheath. NF1 patients were associated with multisystem involvement, characterized by neurofibroma, of which 50% were ...
Mengying Peng, Yuqing Zhang, Qiong Zhou
doaj   +1 more source

Combining SOS1 and MEK Inhibitors in a Murine Model of Plexiform Neurofibroma Results in Tumor Shrinkage

Journal of Pharmacology and Experimental Therapeutics, 2023
Individuals with neurofibromatosis type 1 develop rat sarcoma virus (RAS)–mitogen-activated protein kinase–mitogen-activated and extracellular signal-regulated kinase (RAS-MAPK-MEK)–driven nerve tumors called neurofibromas.
Mark Jackson, Niousha Ahmari, Jianqiang Wu, T. Rizvi, E. Fugate, Mi-Ok Kim, E. Dombi, Heribert Arnhof, G. Boehmelt, M. Düchs, Clive J Long, U. Maier, F. Trapani, M. H. Hofmann, N. Ratner   +14 more
semanticscholar   +1 more source

Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma.

Clinical Cancer Research, 2023
PURPOSE Plexiform neurofibromas (PNF) are peripheral nerve sheath tumors that cause significant morbidity in persons with neurofibromatosis type 1 (NF1), yet treatment options remain limited.
Alyssa C Flint, Dana K. Mitchell, Steve Angus, A. Smith, Waylan K Bessler, Li Jiang, H. Mang, Xiaohong Li, Qingbo Lu, B. Rodriguez, G. Sandusky, A. Masters, Chi Zhang, Pengtao Dang, Jenna K. Koenig, Gary L. Johnson, W. Shen, Jiangang Liu, A. Aggarwal, Gregory P. Donoho, Melinda D Willard, S. Bhagwat, D. Clapp, Steven D. Rhodes   +23 more
semanticscholar   +1 more source

Superimposed Mosaicism in the Form of Extremely Extended Segmental Plexiform Neurofibroma Caused by a Novel Pathogenic Variant in the NF1 Gene

International Journal of Molecular Sciences, 2023
Plexiform neurofibromas occurring in approximately 20–50% of all neurofibromatosis type-1 (NF1) cases are histologically benign tumors, but they can be fatal due to compression of vital structures or transformation to malignant sarcomas or malignant ...
K. Veres, J. Bene, K. Hadzsiev, M. Garami, Sára Pálla, R. Happle, M. Medvecz, Z. Szalai   +7 more
semanticscholar   +1 more source

Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment

JCI Insight, 2022
To define alterations early in tumor formation, we studied nerve tumors in neurofibromatosis 1 (NF1), a tumor predisposition syndrome. Affected individuals develop neurofibromas, benign tumors driven by NF1 loss in Schwann cells (SCs).
Leah J. Kershner, Kwangmin Choi, Jianqiang Wu, Xiyuan Zhang, Melissa R. Perrino, N. Salomonis, J. Shern, N. Ratner   +7 more
semanticscholar   +1 more source