Results 11 to 20 of about 5,977 (216)

Isolated Plexiform Neurofibroma of Arm with Unusual Presentation - A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2015
Plexiform neurofibroma (PNF) arises as a diffuse mass from nerve trunk and leads to overgrowth of cutis and subcutis structure. This is a case report of 20-year-old male, presented to our hospital with a giant ulcerated swelling over his left arm ...
PANKAJ KUMAR MISHRA, RISHI DWIVEDI, DINESH CHANDRA SHRIVASTAVA, SURESH CHANDRA GAUR   +3 more
doaj   +1 more source

Isolated plexiform neurofibroma over left palm: A case report and review of literature

Indian Journal of Dermatology, 2013
Plexiform neurofibroma is common over the branches of trigeminal and cervical nerves over the face. Plexiform neurofibroma over palm is rare and affects the individuals with fine motor functions of hand.
Mohan H Kudur, Manjunath Hulmani
doaj   +1 more source

Lumbar plexiform neurofibroma, short stature, and kyphoscoliosis in neurofibromatosis-1: A Rare entity

Sahel Medical Journal, 2019
The incidence of neurofibromatosis (NF), comprising NF-1 and NF-2, seems to be rising in Nigeria. The features of NF-1 have not been completely identified in the country.
Ernest Ndukaife Anyabolu
doaj   +1 more source

Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients. [PDF]

, 2014
BackgroundGender-based differences in disease onset in murine models of malignant peripheral nerve sheath tumor (MPNST) and in patients with Neurofibromatosis type-1-(NF-1)-associated or spontaneous MPNST has not been well studied.MethodsForty-three ...
Dry, Sarah M, Eilber, Fritz C, Federman, Noah, Li, Yunfeng, Nakashima, Jonathan, Shurell, Elizabeth, Smith, Kathleen B, Tam, Brenna M, Tap, William D, Tran, Linh M, Wu, Hong   +10 more
core   +2 more sources

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. [PDF]

, 2018
Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in Neurofibromin 1 (NF1). NF1 patients present with a variety of clinical manifestations and are predisposed to cancer development.
Carlson, Daniel F, Coutts, Alexander W, Dahiya, Sonika, Dombi, Eva, Fahrenkrug, Scott C, Fisher, James, Giovannini, Marco, Gutmann, David H, Isakson, Sara H, Kirstein, Mark N, Largaespada, David A, Messiaen, Ludwine, Moertel, Christopher L, Pluhar, G Elizabeth, Ratner, Nancy, Rizvi, Tilat, Rizzardi, Anthony E, Stemmer-Rachamimov, Anat O, Vitte, Jeremie, Watson, Adrienne L, Widemann, Brigitte C, Williams, Kyle B   +21 more
core   +2 more sources

Synchronous plexiform neurofibroma in the arytenoids and neurofibroma in the parapharynx in a patient with non-neurofibromatosis: a case report

Journal of Medical Case Reports, 2013
Introduction Plexiform neurofibroma of the larynx is a rare disease. In this report, we present a plexiform neurofibroma in the arytenoids and neurofibroma in the parapharynx detected coincidently.
Son Hee Young, Shim Hyun Seok, Kim Jin Pyeong, Woo Seung Hoon   +3 more
doaj   +1 more source

Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of neurofibromatosis type 1. [PDF]

, 2015
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that predisposes affected individuals to formation of benign neurofibromas, peripheral nerve tumors that can be associated with significant morbidity. Loss of the NF1 Ras-GAP protein causes
Cripe, Timothy P., Dombi, Eva, Dunn, Richard S., Janhofer, David, Jones, David R., Jousma, Edwin, Kim, Mi-Ok, Masters, Andrea R., Ratner, Nancy, Rizvi, Tilat A., Wu, Jianqiang   +10 more
core   +1 more source

Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas [PDF]

, 2015
Plexiform neurofibromas (pNF) are pathognomonic nerve and soft tissue tumors of neurofibromatosis type I (NF1), which are highly resistant to conventional chemotherapy and associated with significant morbidity/mortality.
Chen, Shi, Clapp, D. Wade, Ferguson, Michael J., Hutchins, Gary, Ingram, David A., Jiang, Li, Li, Xiaohong, Rhodes, Steven D., Territo, Paul, Vakili, Saeed T., Yang, Feng-Chun, Yang, Xianlin, Yuan, Jin, Zhang, Shaobo   +13 more
core   +1 more source

Arteriovenous malformation underlying a plexiform neurofibroma: An unusual presentation

Indian Dermatology Online Journal, 2017
Vascular abnormalities associated with neurofibromatosis type 1 are well described in the literature, however, arteriovenous malformation is a very rare finding in neurofibromatosis type 1.
Zaheer Abbas, Sepideh Khani, Javad Zare
doaj   +1 more source

A Rare Tumor in the Neck of a Child: Plexiform Neurofibroma

Turkish Archives of Otorhinolaryngology, 2021
Plexiform neurofibroma represents an uncommon variant of neurofibromatosis type 1, constituting only 5%–30% of all cases. Plexiform neurofibroma is usually diagnosed during childhood and arises from multiple nerves, manifesting as bulging and deforming ...
Siti Sarah Mohd Ramli, Goh Bee See, Faizah Mohd Zaki, Suria Hayati Md Pauzi, Mohamad Fariz Bin Amri   +4 more
doaj   +1 more source