Results 31 to 40 of about 26,212 (200)

Plexiform neurofibroma of the submandibular gland in patient with von Recklinghausen's disease

Rare Tumors, 2011
Plexiform neurofibroma of the submandibular gland is an extremely rare tumor. Herein, we report a case of plexiform neurofibroma in a patient with a von Recklinghausen's disease (NF-1) who presented with a submandibular mass mimicking a submandibular ...
Hassan Al Bisher, Ravi Kant, Ahmed Aldamati, Aysha Ahmed Badar   +3 more
doaj   +1 more source

Massive Plexiform Neurofibroma of the Neck and Larynx

International Archives of Otorhinolaryngology, 2015
Introduction Laryngeal neurofibromas are extremely rare, accounting for only 0.03 to 0.1% of benign tumors of the larynx. Objectives To report the first case of massive neck plexiform neurofibroma with intralaryngeal (supraglottic) extension
Mohammad Kamal Mobashir, Abd ElRaof Said Mohamed, Mohammad Waheed El-Anwar, Ahmad Ebrahim El Sayed, Mouhamad A. Fouad   +4 more
doaj   +1 more source

Features of CT and EUS in mesenteric plexiform neurofibroma with Neurofibromatosis type I: A case report

Radiology Case Reports, 2021
Plexiform neurofibroma(PNF) is a rare benign tumor of the peripheral nerve, belonging to a subtype of neurofibroma. PNF is common in the head, neck and trunk. It is uncommonly observed in the mesentery. We report a case of mesenteric PNF in a 64-year-old
Ye-ting Li, Bachelor's degree, Hao Chen, Master degree, Xue Ding, Master degree, Qian Wu, Bachelor's degree, Qiu-chen Guo, Master degree, Duan-min Hu, PhD, Feng-yun Zhong, PhD, Yong-you Wu, PhD, Guang-qiang Chen, Master degree   +8 more
doaj   +1 more source

Progesterone and Estrogen Receptors in Neurofibromas of Patients with NF1

Clinical Medicine Insights: Pathology, 2008
Neurofibromatosis type 1 (NF1) or von Recklinghausen disease is a genetic disorder affecting the growth of cells in nervous system. One of the most remarkable characteristics of this disease is the development of benign tumors of the nervous system ...
Mauro Geller, Spyros G.E. Mezitis, Fabio Pereira Nunes, Marcia G. Ribeiro, Alexandra Prufer de Q.C. Araújo, Marcello D. Bronstein, Rodrigo Siqueira-Batista, Andréia Patrícia Gomes, Lisa Oliveira, Karin Soares Gonçalves Cunha   +9 more
doaj   +1 more source

Delayed rectifier K currents in NF1 Schwann cells

Neurobiology of Disease, 2003
K+ (K) currents are related to the proliferation of many cell types and have a relationship to second messenger pathways implicated in regulation of the cell cycle in development and certain disease states.
Lynne A Fieber, Diana M González, Margaret R Wallace, David Muir   +3 more
doaj   +1 more source

Plexiform Neurofibroma of Clitoris [PDF]

Journal of Pediatric Genetics, 2017
AbstractThe most frequent genital presentation of neurofibromatosis in females is clitoromegaly. We report a case of a 5-year-old girl with neurofibromatosis type 1 with clitoral plexiform neurofibromatosis. Clitoroplasty was done, and the histopathology confirmed the diagnosis.
Dhanya, Yesodharan, Bindu, Sudarsanan, Annie, Jojo, Mohan, Abraham, Nisha, Bhavani, Hima, Mathews, Sheela, Nampoothiri   +6 more
openaire   +2 more sources

The MEK inhibitor selumetinib reduces spinal neurofibroma burden in patients with NF1 and plexiform neurofibromas.

Neuro-Oncology Advances, 2020
Background Spinal neurofibromas (SNFs) in neurofibromatosis type 1 (NF1) can cause progressive spinal cord compression and neurological dysfunction. The MEK inhibitor selumetinib shrinks the majority of plexiform neurofibromas (PNs) in patients with NF1.
Sadhana Jackson, E. Baker, A. Gross, P. Whitcomb, A. Baldwin, J. Derdak, C. Tibery, J. DeSanto, A. Carbonell, K. Yohay, Geraldine O'Sullivan, A. Chen, B. Widemann, E. Dombi   +13 more
semanticscholar   +1 more source

MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK

Oncogene, 2020
MicroRNAs (miRs) are small non-coding RNAs that can have large impacts on oncogenic pathways. Possible functions of dysregulated miRs have not been studied in neurofibromatosis type 1 (NF1) plexiform neurofibromas (PNFs).
Youjin Na, Ashley Hall, Kwangmin Choi, Liang-liang Hu, J. Rose, Robert Coover, Adam Miller, R. Hennigan, E. Dombi, Mi-Ok Kim, Subbaya Subramanian, N. Ratner, Jianqiang Wu   +12 more
semanticscholar   +1 more source

Malignant transformation in a sciatic plexiform neurofibroma in Neurofibromatosis Type 1 - imaging features that aid diagnosis.

Journal of Radiology Case Reports, 2020
A 41-year-old Asian male with NF1 and bilateral sciatic plexiform neurofibromas, presented with unintentional weight loss, increasing size of a left thigh mass associated with increasing pain and radiculopathy.
Dorinda Chee Yee Chew, Daniel Bin Hang Zhao, K. Sittampalam, S Krishna Kumar   +3 more
semanticscholar   +1 more source

Excision of Solitary Non-syndromic Oral Plexiform Neurofibroma Utilizing a Diode Laser: A Case Report

Cureus
Plexiform neurofibroma is a benign peripheral nerve sheath tumor known to be pathognomonic for neurofibromatosis type 1. However, solitary plexiform neurofibroma in the oral cavity is extremely rare.
Mohammed M Al-Ali, Lubna M. Al-Otaibi, Ibtissam Al-Bakr   +2 more
semanticscholar   +1 more source