Results 21 to 30 of about 19,908 (210)

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. [PDF]

, 2018
Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in Neurofibromin 1 (NF1). NF1 patients present with a variety of clinical manifestations and are predisposed to cancer development.
Carlson, Daniel F, Coutts, Alexander W, Dahiya, Sonika, Dombi, Eva, Fahrenkrug, Scott C, Fisher, James, Giovannini, Marco, Gutmann, David H, Isakson, Sara H, Kirstein, Mark N, Largaespada, David A, Messiaen, Ludwine, Moertel, Christopher L, Pluhar, G Elizabeth, Ratner, Nancy, Rizvi, Tilat, Rizzardi, Anthony E, Stemmer-Rachamimov, Anat O, Vitte, Jeremie, Watson, Adrienne L, Widemann, Brigitte C, Williams, Kyle B   +21 more
core   +2 more sources

Solitary neurofibroma in the male breast [PDF]

, 2007
BACKGROUND: Neurofibroma of the male breast outside of neurofibromatosis is extremely rare with only one previous case having been reported. CASE PRESENTATION: A 48 year old male patient with a neurofibroma in the breast presenting with gynaecomastia is ...
Deva S Jeyaretna, Adewunmi Oriolowo, Mark EF Smith, Roger M Watkins, YL Hock, JE Sherman, CDM Fletcher, D Laky, AS Narayan, ES Wargotz, RA Cooper, M Al-Qattan   +11 more
core   +3 more sources

Cellular Neurofibroma with Atypia Mimics Sarcoma: Report of a Case with Immunohistochemical Staining Pattern Analysis and Literature Review

Kaohsiung Journal of Medical Sciences, 2006
A case of two sporadic cellular neurofibromas with atypia and one widespread hyalinization neurofibroma of the lumbar spine in a 51-year-old man without evidence of neurofibromatosis-1 is reported. Cellular neurofibroma with atypia is an unusual variant.
Shih-Wen Hu, Shiuh-Lin Hwang, Wei-Chen Lin, Kun-Bow Tsai   +3 more
doaj   +1 more source

TYK2 promotes malignant peripheral nerve sheath tumor progression through inhibition of cell death [PDF]

, 2019
BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise most commonly in the setting of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome.
Bu, Xianzhang, Godec, Abigail, Hirbe, Angela C, Qin, Wenjing, Shao, Jieya, Tao, Yu, Zhang, Xiaochun, Zhu, Cuige   +7 more
core   +2 more sources

Pigmented neurofibroma of the skin

Archives of Medicine and Health Sciences, 2015
Pigmented neurofibroma is a rare variant of neurofibroma commonly associated with neurofibromatosis 1 of diffuse type. Histopathologic examination is essential to differentiate it from other pigmented lesions.
Hemalata Mahantappa, Suguna Belur Venugopal, Swati Agarwal   +2 more
doaj   +1 more source

Solitary intraosseous neurofibroma of the mandible. Apropos of a case [PDF]

, 2011
Neurofibroma is a benign neoplasm derived from peripheral nerves. Most of these are associated with Neurofibromatosis but may also occur as solitary lesions. When found on the head and neck they are generally located in the soft tissue.
Deichler, Javiera, Esguep, Alfredo, Marshall, Maureen, Martínez, René, Niklander, Sven, Seguel, Heraldo   +5 more
core   +1 more source

Neurofibroma of the Lingual Nerve: A Case Report

Kaohsiung Journal of Medical Sciences, 2006
A neurofibroma of the lingual nerve is a rare clinical finding, the most common lesion site of a lingual neurofibroma being the tongue. In most situations, it is difficult to determine the precise nerve origins.
Hsun-Mo Wang, Ying-Che Hsu, Ka-Wo Lee, Feng-Yu Chiang, Wen-Rei Kuo   +4 more
doaj   +1 more source

Pigmented neurofibroma with hypertrichosis

Boletín Médico del Hospital Infantil de México, 2023
Background: Pigmented (or melanocytic) neurofibroma (PN) constitutes only 1% of cases and is considered a rare variant of neurofibroma containing melanin-producing cells. In addition, the association of PN with hypertrichosis is infrequent.
Juan A. Godínez-Chaparro, Adriana M. Valencia-Herrera, Carlos A. Mena-Cedillos, Sonia Toussaint-Caire, Mario R. Duarte-Abdala, Omar Loza-Escutia, Mirna E. Toledo-Bahena   +6 more
doaj   +1 more source

Voice characteristics in adults with neurofibromatosis type 1 [PDF]

, 2010
Introduction and aims of the study: Change or loss of voice in patients with neurofibromatosis type 1 (NF1) has been associated with head and neck neurofibromas.
Corthals, Paul, Cosyns, Marjan, Janssens, Sandra, Mortier, Geert, Van Borsel, John   +4 more
core   +2 more sources

Revisiting the NPcis mouse model: A new tool to model plexiform neurofibroma.

PLoS ONE
Neurofibromatosis Type I (NF1) is a rare genetic disorder. NF1 patients frequently develop a benign tumor in peripheral nerve plexuses called plexiform neurofibroma.
Camille Plante, Teddy Mohamad, Dhanushka Hewa Bostanthirige, Michel Renaud, Harsimran Sidhu, Michel ElChoueiry, Jean-Paul Sabo Vatasescu, Mikael Poirier, Sameh Geha, Jean-Philippe Brosseau   +9 more
doaj   +1 more source