Results 11 to 20 of about 1,400 (148)

Prevalence of Oral Alterations and Correlation Between Oral and Cutaneous Neurofibromas in Neurofibromatosis Type 1: A Retrospective Case-Control Study. [PDF]

J Oral Pathol Med
ABSTRACT Objective The aim of this study was to determine the prevalence of oral alterations detectable through physical examination in NF1 individuals. Additionally, we assessed the correlation between the number of oral and cutaneous neurofibromas. Design This retrospective study evaluated oral alterations in individuals with and without NF1.
de Pinho Montovani P, da Costa GPWM, Rozza-de-Menezes RE, Cunha KS.   +3 more
europepmc   +2 more sources

Heterozygous NF1 dermal fibroblasts modulate exosomal content to promote angiogenesis in a tissue‐engineered skin model of neurofibromatosis type‐1

Journal of Neurochemistry, Volume 167, Issue 4, Page 556-570, November 2023., 2023
In this study, we investigated the influence of dermal fibroblast in modifying the surrounding microenvironment. Neovascularization plays a crucial role in neurofibromas formation, growth, and malignant transformation. Using NF1‐derived tissue‐engineered skins, we showed that NF1 heterozygosity in human dermal fibroblasts promoted angiogenesis through ...
Vincent Roy, Alexandre Paquet, Lydia Touzel‐Deschênes, Hélène T. Khuong, Nicolas Dupré, Francois Gros‐Louis   +5 more
wiley   +1 more source

Pharmacology of inhibitors of Janus kinases – Part 2: Pharmacodynamics

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 12, Page 1621-1631, December 2022., 2022
Summary As small molecules, the Janus kinase inhibitors have different, dose‐dependent pharmacological binding selectivities, which, however, do not allow reliable statements about the clinical specificity of desired or side effects. It is therefore of particular importance to recognize that the pharmacodynamics of the individual Janus kinase ...
Adina Eichner, Johannes Wohlrab
wiley   +1 more source

Das Spektrum melanozytärer Nävi und deren klinische Bedeutung

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 4, Page 483-506, April 2022., 2022
Zusammenfassung Die Größe der Thematik melanozytärer Nävi (MN) steht in einem direkten Verhältnis zur Relevanz in der alltäglichen klinischen Arbeit. Die klinische Präsentation ist hochgradig variabel und verschiedene MN haben unterschiedliche prognostische Bedeutung in Bezug auf Komorbidität und mögliches Entartungsrisiko.
Nina Frischhut, Bernhard Zelger, Fiona Andre, Bettina Gudrun Zelger   +3 more
wiley   +1 more source

Abordagem cirúrgica de neurofibroma gigante Surgical correction of a giant neurofibroma

Revista Brasileira de Cirurgia Plástica, 2012
Neurofibromatose é uma doença de origem genética autossômica dominante composta por três tipos: neurofibromatose tipo 1 (NF1), neurofibromatose tipo 2 (NF2) e schwannomatose.
Iana Silva Dias, Salustiano Gomes de Pinho Pessoa, José Everardo Macedo, Débora Juaçaba Cavalcante, Júlio César Garcia de Alencar   +4 more
doaj   +1 more source

Ipsilateral Vestibular Schwannoma after Cochlear Implantation

Case Reports in Otolaryngology, Volume 2022, Issue 1, 2022., 2022
Objective. The vestibular schwannoma incidence rate is approximately 4.2 per 100,000/year. Thus far, about 700,000 cochlear implantations have been performed worldwide; therefore, the occurrence of vestibular schwannoma postcochlear implantations can be assumed to be infrequent.
S. Tüpker, N. Ay, L. U. Scholtz, H. B. Gehl, V. F. Mautner, P. Goon, H. Sudhoff, I. Todt, Toshihisa Murofushi   +8 more
wiley   +1 more source

Síndrome de moyamoya associada a neurofibromatose tipo I em paciente pediátrico [PDF]

, 2011
CONTEXT: Neurofibromatosis type 1 (NF-1) is the most prevalent autosomal dominant genetic disorder among humans. Moyamoya disease is a cerebral vasculopathy that is only rarely observed in association with NF-1, particularly in the pediatric age range ...
DARRIGO JÚNIOR, Luiz Guilherme, MACHADO, André de Aboim, SANTOS, Antonio Carlos dos, SCRIDELI, Carlos Alberto, TONE, Luiz Gonzaga, VALERA, Elvis Terci   +5 more
core   +1 more source

Meningoceles intratorácicas gigantes associadas a neurofibromatose tipo I: relato de caso [PDF]

, 2003
BACKGROUND: Intrathoracic meningocele is a rare pathology, almost always associated with neurofibromatosis type I and with a few cases related in the literature.
Andrade, Guilherme Cabral de, Braga, Fernando Menezes, Braga, Otávio Piccirillo, Hisatugo, Marcelo Ken-Iti, Paiva Neto, Manoel Antonio de, Succi, Ernesto   +5 more
core   +3 more sources

Mécanismes et conséquences des mutations [PDF]

, 2005
L’identification des mutations à l’origine de maladies génétiques chez l’homme a pris ces dernières années un essor considérable. Il est devenu possible d’établir le spectre des mutations délétères pour une maladie génétique donnée, et des bases de ...
Hanna, Nadine, Parfait, Béatrice, Vidaud, Dominique, Vidaud, Michel   +3 more
core   +1 more source

Syndrome in question [PDF]

, 2016
Neurofibromatosis is extremely variable in its presentation. Segmental neurofibromatosis (SNF), which corresponds to NF-type 5 in the Riccardi classification, is a rare disorder. It may go unrecognized if few lesions are observed.
Carvalho, S., Horta, M., Oujo, E., Rosmaninho, A.   +3 more
core   +3 more sources