Strangled by His Nerves—Cervical Plexiform Neurofibroma With Infantile Spinal Neurofibromatosis: Case Report in a 14 Years Old Child [PDF]
Clinical Medicine Insights: Case Reports, 2023 Background: Neurofibromatoses are a rare group of autosomal dominant tumor suppressor phacomatoses syndromes. Neurofibromatosis type 1 (NF1 or Von Recklinghausen’s disease) is the most commonly found type of neurofibromatosis, and constitutes the most ...
Ilias Tahiri +8 more
doaj +2 more sources
Targeted Therapies for the Neurofibromatoses [PDF]
Cancers, 2021 Over the past several years, management of the tumors associated with the neurofibromatoses has been recognized to often require approaches that are distinct from their spontaneous counterparts. Focus has shifted to therapy aimed at minimizing symptoms given the risks of persistent, multiple tumors and new tumor growth.
Lauren Dengle Sanchez +2 more
exaly +3 more sources
An Unexplored Diversity for Adaptation of Germination to High Temperatures in <i>Brassica</i> Species. [PDF]
Evol ApplABSTRACT Elevated temperatures inhibit the germination of a concerning number of crop species. One strategy to mitigate the impact of warming temperatures is to identify and introgress adaptive genes into elite germplasm. Diversity must be sought in wild populations, coupled with an understanding of the complex pattern of adaptation across a broad ...
Tiret M +10 more
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Neurofibromatosis: New Clinical Challenges in the Era of COVID-19 [PDF]
Biomedicines, 2022 Rare diseases constitute a wide range of disorders thus defined for their low prevalence. However, taken together, rare diseases impact a considerable percentage of the world population, thus representing a public healthcare problem.
Alessio Ardizzone +5 more
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Neurofibromatoses: part 1 ? diagnosis and differential diagnosis
Arquivos De Neuro-Psiquiatria, 2014 Neurofibromatoses (NF) are a group of genetic multiple tumor growing predisposition diseases: neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH), which have in common the neural origin of tumors and cutaneous signs ...
Luiz Darrigo Junior +2 more
exaly +3 more sources
Lymphoproliferative malignancies in patients with neurofibromatosis 1 [PDF]
Orphanet Journal of Rare Diseases, 2021 Neurofibromatosis 1 (NF1) is an inherited, autosomal-dominant, tumor predisposition syndrome with a birth incidence as high as 1:2000. A patient with NF1 is four to five times more likely to develop a malignancy as compared to the general population. The
Christina Bergqvist +4 more
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Comparing 3D imaging devices for the measurement of cutaneous neurofibromas in patients with Neurofibromatosis Type 1. [PDF]
Skin Res TechnolAbstract Background Cutaneous neurofibromas (cNFs) are a major cause of disfigurement in patients with Neurofibromatosis Type 1 (NF1). However, clinical trials investigating cNF treatments lack standardised outcome measures to objectively evaluate changes in cNF size and appearance.
Lau JCL +12 more
europepmc +2 more sources
Development of an adult neurofibromatosis clinic in the comprehensive cancer center setting and descriptive analysis of the first 100 patients with neurofibromatosis type 1 [PDF]
Orphanet Journal of Rare DiseasesBackground Neurofibromatosis type 1 is a multisystem genetic disorder that most commonly presents with dermatologic manifestations, while also involving the central and peripheral nervous systems.
Lindsay J. Lipinski +9 more
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Radiofrequency Ablation and Excision of Multiple Cutaneous Lesions in Neurofibromatosis Type 1 [PDF]
Archives of Plastic Surgery, 2013 Background Von Recklinghausen disease or neurofibromatosis type 1 is an autosomal dominant genetic disorder of chromosome 17q11.2. The most common characteristic findings of NF 1 include multiple and recurrent cutaneous neurofibromas associated with ...
Seong-Hun Kim +3 more
doaj +2 more sources