Results 21 to 30 of about 922 (157)

Heterozygous NF1 dermal fibroblasts modulate exosomal content to promote angiogenesis in a tissue‐engineered skin model of neurofibromatosis type‐1

Journal of Neurochemistry, Volume 167, Issue 4, Page 556-570, November 2023., 2023
In this study, we investigated the influence of dermal fibroblast in modifying the surrounding microenvironment. Neovascularization plays a crucial role in neurofibromas formation, growth, and malignant transformation. Using NF1‐derived tissue‐engineered skins, we showed that NF1 heterozygosity in human dermal fibroblasts promoted angiogenesis through ...
Vincent Roy, Alexandre Paquet, Lydia Touzel‐Deschênes, Hélène T. Khuong, Nicolas Dupré, Francois Gros‐Louis   +5 more
wiley   +1 more source

Neurofibromatoses

, 2010
Gregory K Kim
exaly   +2 more sources

Dermoscopy of the iris: identification of Lisch nodules and contribution to the diagnosis of neurofibromatosis type 1

Anais Brasileiros de Dermatologia, 2021
Neurofibromatosis is a common genodermatosis, whose diagnosis often involves the participation of a dermatologist. A case of a 38-year-old female patient with four café-au-lait macules and eleven neurofibromas on clinical examination is presented ...
Luciana Pavan Antoniolli, Laura de Mattos Milman, Renan Rangel Bonamigo   +2 more
doaj   +1 more source

A unique case of hereditary bilateral segmental neurofibromatosis on the face Neurofibromatose segmentar bilateral hereditária da face: caso único

Anais Brasileiros de Dermatologia, 2012
Segmental neurofibromatosis is a rare clinical finding generally with no family history and facial involvement. There are four subtypes of segmental neurofibromatosis: true segmental, localized cases with deep involvement, hereditary segmental and ...
Irena Jankovic, Predrag Kovacevic, Milan Visnjic, Dimitrije Jankovic, Milena Velickovic   +4 more
doaj   +1 more source

Ophthalmological Issues in the Neurofibromatoses

Journal of Pediatric Ophthalmology and Strabismus, 1996
Bruce R. Korf
exaly   +2 more sources

Neurofibromatoses in Clinical Practice

, 2011
Susan M Huson, D Gareth R Evans
exaly   +2 more sources

Comparing 3D imaging devices for the measurement of cutaneous neurofibromas in patients with Neurofibromatosis Type 1. [PDF]

Skin Res Technol
Abstract Background Cutaneous neurofibromas (cNFs) are a major cause of disfigurement in patients with Neurofibromatosis Type 1 (NF1). However, clinical trials investigating cNF treatments lack standardised outcome measures to objectively evaluate changes in cNF size and appearance.
Lau JCL, Fleming J, Good M, Lim A, Saunderson RB, Phan TA, Schlub T, Siow SF, Lacson N, Romo C, Blakely J, Bergqvist C, Berman YD.   +12 more
europepmc   +2 more sources

Prenatal Diagnosis of the Neurofibromatoses

Clinics in Perinatology, 1990
Stefan-Matthias Pulst
exaly   +2 more sources

Neurofibromatose tipo 1: relato de um caso clínico

Revista Portuguesa de Medicina Geral e Familiar, 2013
Introdução: A neurofibromatose tipo 1 (NF1) é uma doença neurocutânea de hereditariedade autossómica dominante, ocorrendo mutações de novo em cerca de metade dos casos.
Ana Catarina Marques, Fátima Dinis
doaj   +1 more source

Mouse Models of Neurofibromatosis 1 and 2

Neoplasia: An International Journal for Oncology Research, 2002
The neurofibromatoses represent two of the most common inherited tumor predisposition syndromes affecting the nervous system. Individuals with neurofibromatosis 1 (NF1) are prone to the development of astrocytomas and peripheral nerve sheath tumors ...
David H. Gutmann, Marco Giovannini
doaj   +1 more source