Results 131 to 140 of about 24,619,681 (234)

Regulation of ER Stress‐Associated Gene Expression by Lifeguard in Human Breast Cancer Cells

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Despite significant advances in breast cancer therapy, resistance to apoptosis remains a major obstacle to successful treatment. Lifeguard (LFG), an antiapoptotic membrane protein, has been implicated in breast cancer progression; however, its role in endoplasmic reticulum (ER) stress‐associated molecular responses and apoptosis ...
Inga Nebel, Sarah Strauß, Frederik Schlottmann, Lena Maria Herrmann, Peter M. Vogt, Vesna Bucan   +5 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

A Diagnostic Challenge: Unilateral Gingival Enlargement With Altered Tooth Eruption in a Paediatric Patient

Oral Diseases, EarlyView.
Luca Cricenti, Rossella Ninivaggi, Federico Liguori, Nicola Scotti, Allegra Comba, Patrizia Defabianis, Federica Romano   +6 more
wiley   +1 more source

Digital health interventions for psychological and cognitive care in cancer patients and caregivers: A RE‐AIM‐based systematic review

Applied Psychology: Health and Well-Being, Volume 18, Issue 5, October 2026.
Abstract Beyond physical challenges, cancer can cause psychological and cognitive challenges for patients, caregivers, and family members. Digital health interventions show promise in addressing these issues. However, evidence on their applicability in daily cancer care is limited. The objective of this systematic review is to evaluate the internal and
Melissa Heifez, Laura Ciria‐Suarez, Sara Martín‐Parra, Ilaria Durosini, Dario Monzani, Veronica Coppini, Maria Vittoria Ferrari, Mareike Rutenkröger, Marie Lange, Nikolina Dodlek, Lotte van der Weijst, Andreas Charalambous, Marta Perez‐Campdepadrós, Derek Clougher, Miguel Angel Orrego, Gabriella Pravettoni, Cristian Ochoa‐Arnedo   +16 more
wiley   +1 more source

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 10, October 2026.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart, Lawrence Mbuagbaw, Joseph Beyene, Marwa Akola, Sarah Burrow, M. Constantine Samaan, Lehana Thabane, Adam Fleming, Donna L. Johnston, Shahrad R. Rassekh, Laura Banfield, Russell J. de Souza   +11 more
wiley   +1 more source

Neurofibromatosis tipos 1 y 2

Revista del Hospital Italiano de Buenos Aires
La neurofibromatosis (NF) comprende un grupo de enfermedades genéticas de herencia autosómica dominante, que se clasifican de la siguiente manera: neurofibromatosis tipo 1 (NF1), neurofibromatosis tipo 2 (NF2) y schwannomatosis (también conocida como ...
María Florencia Correa, Natalia Inés Pasik   +1 more
doaj  

Neurofibromatosis: an update of ophthalmic characteristics and applications of optical coherence tomography

, 2016
Barmak Abdolrahimzadeh,1 Domenica Carmen Piraino,2 Giorgio Albanese,2 Filippo Cruciani,2 Siavash Rahimi3 1Polimed Beltramelli Medical Center, Rome, Italy; 2Section of Ophthalmology, Department of Sense Organs, University of Rome “Sapienza&rdquo ...
Rahimi S, Albanese G, Piraino DC, Abdolrahimzadeh B, Cruciani F   +4 more
core  

Abordaje clínico de variantes fenotípicas en neurofibromatosis de tipo 1 [PDF]

, 2019
Neurofibromatosis type 1 is an autosomal dominant disorder, with multisystemic affectation and high phenotypic variation, caused by NF1 mutation in the locus 17 q11.2 that codes for neurofibromin.The estimated prevalence of people affected by this ...
López, Jairo Enrique, Vallejo, Dora Lucía   +1 more
core  

Segmental neurofibromatosis: A report of 3 cases

Indian Journal of Dermatology, 2010
Neurofibromatosis is a genetic disorder of neural crest-derived cells that primarily affect growth of neural tissues. It is broadly divided into three categories: (a) von Recklinghausen′s neurofibromatosis or NF-1, (b) bilateral acoustic neuroma ...
Gabhane Sushma, Kotwal Mrunmayi, Bobhate Sudhakar   +2 more
doaj  

Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2). [PDF]

BMC Pharmacol Toxicol, 2019
Shen YC, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF.   +8 more
europepmc   +1 more source