Results 71 to 80 of about 102,686 (380)
Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression
Movement Disorders, 2020 The objective of this study was to assess neurofilament light chain as a Parkinson's disease biomarker.
B. Mollenhauer +25 more
semanticscholar +1 more source
Anesthesiology, 2022 Background: Neurofilament light is a marker of neuronal injury and can be measured in blood. Postoperative increases in neurofilament light have been associated with delirium after noncardiac surgery. However, few studies have examined the association of
Charles H. Brown +10 more
semanticscholar +1 more source
Biomarkers and the Development of a Personalized Medicine Approach in Spinal Muscular Atrophy
Frontiers in Neurology, 2019 Recent unprecedented advances in treatment for spinal muscular atrophy (SMA) enabled patients to access the first approved disease modifying therapy for the condition.
Didu S. T. Kariyawasam +6 more
doaj +1 more source
Retinal and Optic Nerve Integrity Following Monocular Inactivation for the Treatment of Amblyopia
Frontiers in Systems Neuroscience, 2020 In animal models, monocular deprivation (MD) by lid closure mimics the effects of unilateral amblyopia in humans. Temporary inactivation of one or both eyes with intraocular administration of tetrodotoxin (TTX) has recently been shown to promote recovery
Nadia R. DiCostanzo +3 more
doaj +1 more source
A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]
, 2018 The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria +11 more
core +2 more sources
SARM1 Depletion Slows Axon Degeneration in a CNS Model of Neurotropic Viral Infection
Frontiers in Molecular Neuroscience, 2022 Zika virus (ZIKV) is a neurotropic flavivirus recently linked to congenital ZIKV syndrome in children and encephalitis and Guillain-Barré syndrome in adults. Neurotropic viruses often use axons to traffic to neuronal or glial cell somas where they either
Colin L. Crawford +13 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Cell lineage analysis of the avian neural crest [PDF]
, 1991 Neural crest cells migrate extensively and give rise to diverse cell types, including cells of the sensory and autonomic nervous systems. A major unanswered question concerning the neural crest is when and how the neural crest cells become determined to ...
Bronner-Fraser, Marianne +1 more
core
Fingolimod modulates microglial activation to augment markers of remyelination [PDF]
, 2011 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Baker, D, Giovannoni, G, Jackson, SJ
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source