Results 81 to 90 of about 65,054 (212)

Neurofilament light as a prognostic marker in multiple sclerosis

open access: yes, 2010
Relapsing-remitting multiple sclerosis has a variable prognosis and lacks a reliable laboratory prognostic marker. Our aim in this study was to investigate the association between neurofilament light levels in cerebrospinal fluid in early multiple ...
Sundström, Peter,   +2 more
core   +1 more source

Slow axonal transport of neurofilament protein in cultured neurons

open access: yes, 1999
We have investigated the axonal transport of neurofilament protein in cultured neurons by constrict-ing single axons with fine glass fibers. We observed a rapid accumulation of anterogradely and retrogradely transported membranous organelles on both ...
Thomas J. Koehnle, Anthony Brown
core  

Neurofilament gene expression in Alzheimer's disease [PDF]

open access: yes, 1990
In order to investigate the role of cytoskeletal genes in Alzheimer's disease(AD), we studied the expression of genes coding for actin, tubulin and neurofilament genes in brain tissues from Alzeimer's disease patients and normal controls using northern ...
Marksberry, William   +5 more
core   +1 more source

Circulating neurofilaments to track dorsal root ganglion toxicity risks with AAV-mediated gene therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2022
Michelle A. Farrar   +2 more
doaj   +1 more source

Dietary vitamin K intake is associated with decreased neurofilament light chain among middle-aged and older adults from the NHANES

open access: yesFrontiers in Nutrition
PurposeNeurofilament-light chain (NfL) is associated with neurodegenerative diseases, which are increasingly prevalent with aging. Vitamin K has been shown a neuroprotective effect.
Jing Luo, Song Lin
doaj   +1 more source

Plasma neurofilament light change with hemoglobin A1c by ethnic group.

open access: yes
Plasma neurofilament light change with hemoglobin A1c by ethnic group.
Molly Maxfield (9916890)   +7 more
core   +1 more source

Longitudinal profile of plasma neurofilament light chain levels in 16 sepsis patients with brain dysfunction and four patients without brain dysfunction.

open access: yes, 2019
NfL levels significantly increased in patients with brain dysfunction over time which was not observed in patients without brain dysfunction. Bold line indicates the development of mean plasma neurofilament levels over time. NfL Neurofilament light.
Jörg Henschel (6260915)   +14 more
core   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

open access: yesAnnals of Clinical and Translational Neurology
Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the ...
Maximilian Einsiedler   +43 more
doaj   +1 more source

Plasma neurofilament light change with blood glucose by ethnic group.

open access: yes
Plasma neurofilament light change with blood glucose by ethnic group.
Molly Maxfield (9916890)   +7 more
core   +1 more source

Bcl-2 Overexpression Does Not Protect Neurons from Mutant Neurofilament-Mediated Motor Neuron Degeneration

open access: yes, 1999
Transgenic mice with a point mutation in the light neurofilament gene develop amyotrophic lateral sclerosis–like motor neuron disease characterized by selective spinal motor neuron loss, neurofilamentous accumulations, and severe muscle atrophy.
Don W. Cleveland, Megan K. Houseweart
core   +1 more source

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