Results 71 to 80 of about 65,054 (212)
Tetanus toxin and neurofilament antisera stained cultured neurons of rat embryo in a similar pattern. However, some neuronal processes were stained only by one of these antisera, and bright neurofilament-positive large neurons present in late cultures ...
Raju, T. R., Dahl, D.
core +1 more source
Neurofilament light chain as a biomarker for acute hepatic porphyrias
BackgroundAcute hepatic porphyrias (AHP) represent a rare group of inherited metabolic disorders of heme biosynthesis pathway. This study aims to determine the diagnostic and prognostic value of serum neurofilament light chain (NfL) as potential ...
Paulo Sgobbi +10 more
doaj +1 more source
(1) Background: Multiple sclerosis (MS) is a biologically highly heterogeneous disease and has poor predictability at diagnosis. Moreover, robust data indicate that early disease activity strongly correlates with future disability.
Eleonora Virgilio +12 more
doaj +1 more source
A new marker for ischemic cerebrovascular stroke: Phosphorylated Neurofilament H
Background and purposeA main problem in patients with ischemic CVS is the absence of a blood marker that can be collected to diagnose and predict prognosis.
Hamdy Saber +3 more
core +1 more source
IntroductionNeuropsychiatric systemic lupus erythematosus (NPSLE) is a major clinical challenge, characterized by heterogeneous manifestations and the absence of reliable biomarkers.
Karim Matmat +10 more
doaj +1 more source
Neurofilament homeostasis and motoneurone degeneration.
Neurofilament disorganisation is a hallmark of various neurodegenerative diseases. We review here current knowledge of neurofilament structure, gene expression and function.
PernasAlonso R +2 more
core
Neurofilament IR in the lesioned nerve.
(A) Neurofilament IR in axons distal and proximal to the lesion site 13 days after SNC. (B) Neurofilament IR levels recovered more slowly in GFAP–/–Vim–/– (n = 5) than WT (n = 5) mice.
Ulrika Wilhelmsson (365378) +5 more
core +1 more source
ObjectiveEstablishing biomarkers to predict multiple sclerosis (MS) disability accrual has been challenging using a single biomarker approach, likely due to the complex interplay of neuroinflammation and neurodegeneration.
Vinzenz Fleischer +11 more
doaj +1 more source
Regional modulation of neurofilament organization by myelination in normal axons
Previous studies in the hypomyelinating mouse mutant Trembler have suggested that demyelinating axons are smaller in caliber compared to normal axons, and that there are differences in the organization of axonal neurofilaments. In the normal PNS, however,
BD Trapp +7 more
core +1 more source
BackgroundNeurofilament light chain levels (NfL) have emerged as a biomarker for early diagnosis and follow-up of hereditary transthyretin variant amyloidosis (ATTRv). We evaluated the most accurate technique for NfL quantifying in ATTRv healthy carriers
Álvaro Gragera-Martínez +19 more
doaj +1 more source

