Results 71 to 80 of about 65,054 (212)

Immunofluorescence staining of cultured neurons: a comparative study using tetanus toxin and neurofilament antisera

open access: yes, 1982
Tetanus toxin and neurofilament antisera stained cultured neurons of rat embryo in a similar pattern. However, some neuronal processes were stained only by one of these antisera, and bright neurofilament-positive large neurons present in late cultures ...
Raju, T. R., Dahl, D.
core   +1 more source

Neurofilament light chain as a biomarker for acute hepatic porphyrias

open access: yesFrontiers in Neurology
BackgroundAcute hepatic porphyrias (AHP) represent a rare group of inherited metabolic disorders of heme biosynthesis pathway. This study aims to determine the diagnostic and prognostic value of serum neurofilament light chain (NfL) as potential ...
Paulo Sgobbi   +10 more
doaj   +1 more source

The Association of Axonal Damage Biomarkers and Osteopontin at Diagnosis Could Be Useful in Newly Diagnosed MS Patients

open access: yesNeurology International
(1) Background: Multiple sclerosis (MS) is a biologically highly heterogeneous disease and has poor predictability at diagnosis. Moreover, robust data indicate that early disease activity strongly correlates with future disability.
Eleonora Virgilio   +12 more
doaj   +1 more source

A new marker for ischemic cerebrovascular stroke: Phosphorylated Neurofilament H

open access: yes, 2013
Background and purposeA main problem in patients with ischemic CVS is the absence of a blood marker that can be collected to diagnose and predict prognosis.
Hamdy Saber   +3 more
core   +1 more source

IFNγ-associated immune–metabolic remodeling is linked to serotonin–kynurenine imbalance and cortical vulnerability in lupus-prone mice

open access: yesFrontiers in Immunology
IntroductionNeuropsychiatric systemic lupus erythematosus (NPSLE) is a major clinical challenge, characterized by heterogeneous manifestations and the absence of reliable biomarkers.
Karim Matmat   +10 more
doaj   +1 more source

Neurofilament homeostasis and motoneurone degeneration.

open access: yes, 2001
Neurofilament disorganisation is a hallmark of various neurodegenerative diseases. We review here current knowledge of neurofilament structure, gene expression and function.
PernasAlonso R   +2 more
core  

Neurofilament IR in the lesioned nerve.

open access: yes, 2013
(A) Neurofilament IR in axons distal and proximal to the lesion site 13 days after SNC. (B) Neurofilament IR levels recovered more slowly in GFAP–/–Vim–/– (n = 5) than WT (n = 5) mice.
Ulrika Wilhelmsson (365378)   +5 more
core   +1 more source

Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis

open access: yesFrontiers in Immunology
ObjectiveEstablishing biomarkers to predict multiple sclerosis (MS) disability accrual has been challenging using a single biomarker approach, likely due to the complex interplay of neuroinflammation and neurodegeneration.
Vinzenz Fleischer   +11 more
doaj   +1 more source

Regional modulation of neurofilament organization by myelination in normal axons

open access: yes, 1994
Previous studies in the hypomyelinating mouse mutant Trembler have suggested that demyelinating axons are smaller in caliber compared to normal axons, and that there are differences in the organization of axonal neurofilaments. In the normal PNS, however,
BD Trapp   +7 more
core   +1 more source

Clinical utility of neurofilament light chain as a biomarker for disease onset and progression in hereditary transthyretin amyloidosis

open access: yesFrontiers in Neurology
BackgroundNeurofilament light chain levels (NfL) have emerged as a biomarker for early diagnosis and follow-up of hereditary transthyretin variant amyloidosis (ATTRv). We evaluated the most accurate technique for NfL quantifying in ATTRv healthy carriers
Álvaro Gragera-Martínez   +19 more
doaj   +1 more source

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