Results 281 to 290 of about 50,787 (316)

Stable isotope labelling kinetics of neurofilament light. [PDF]

Brain Commun
Leckey CA, Giovannucci TA, Coulton JB, He Y, Sato C, Ghoshal N, Vignarajah T, Jaunmuktane Z, Barthélemy NR, Zetterberg H, Elbert DL, Mills K, Wray S, Bateman RJ, Paterson RW.   +14 more
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Combined use of plasma p-tau217, NfL, and GFAP predicts domain-specific cognitive decline in cognitively unimpaired and MCI individuals. [PDF]

Alzheimers Dement
Wu CY, Chen L, Fatima H, Gatchel J, Das S, Kivisäkk P, Arnold SE, Dodge HH.   +7 more
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Alzheimer's Disease-Associated Molecular Abnormalities in White Matter Glia and Related Pathologies Detected in Unfractionated and O4-Selected Serum Exosomes Using a Liquid Biopsy Approach. [PDF]

Biomedicines
de la Monte SM, Tong M.
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Neurofilament protein synthesis and phosphorylation

Journal of Neurocytology, 2000
Neurofilament proteins, a major intermediate filament component of the neuronal cytoskeleton, are organized as 10 nm thick filaments in axons and dendrites. They are large, abundantly phosphorylated proteins with numerous phosphate acceptor sites, up to 100 in some cases, organized as numerous repeat motifs.
P, Grant, H C, Pant
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Expanded Polyglutamine Domain Proteins Bind Neurofilament and Alter the Neurofilament Network

Experimental Neurology, 1999
Eight inherited neurodegenerative diseases are caused by genes with expanded CAG repeats coding for polyglutamine domains in the disease-producing proteins. The mechanism by which this expanded polyglutamine domain causes neurodegenerative disease is unknown, but nuclear and cytoplasmic polyglutamine protein aggregation is a common feature.
Y, Nagai, O, Onodera, J, Chun, W J, Strittmatter, J R, Burke   +4 more
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Structural homologies in mammalian neurofilament proteins

Brain Research, 1977
Antibody has been prepared to purified neurofilament protein extracted from calf brain. This antibody crossreacts with brain and nerve extracts from all mammals tested but fails to crossreact with frog, cod and chicken nerve extracts. Thus the serologic homology of these neurofilament proteins appears to be restricted to the mammals.
P F, Davison, B S, Hong
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Ca2+ binding by Myxicola neurofilament proteins

Cell Calcium, 1990
Titrimetric, 45Ca dialysis, and autoradiographic methods were used to examine how axoplasmic proteins from the giant neuron of the marine annelid Myxicola infundibulum bind calcium. Following the autoradiographic method of Maruyama et al., the 150-160 kD neurofilament subunits were identified as prominent intracellular Ca-binding peptides.
R F, Abercrombie, N F, al-Baldawi, J, Jackson   +2 more
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Neurofilament Proteins in Cultured Chromaffin Cells

Journal of Neurochemistry, 1984
Abstract: Antibodies were raised against the 200‐kd, 145‐kd, and 68‐kd subunits of a rat neurofilament preparation. Immunoblots showed that each antibody was specific for its antigen and that it did not cross‐react with any of the two other neurofilament polypeptides.
M F, Bader, E, Georges, W E, Mushynski, J M, Trifaró   +3 more
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Polyglutamine Domain Proteins with Expanded Repeats Bind Neurofilament, Altering the Neurofilament Network

Annals of the New York Academy of Sciences, 1999
ABSTRACT: Proteins with expanded polyglutamine (polyQ) repeats cause eight inherited neurodegenerative diseases. Nuclear and cytoplasmic polyQ protein is a common feature of these diseases, but its role in cell death remains debatable. Since the neuronal intermediate filament network is composed of neurofilament (NF) and NF abnormalities occur in ...
Y, Nagai, O, Onodera, W J, Strittmatter, J R, Burke   +3 more
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