Results 131 to 140 of about 218,517 (358)
Unsupervised learning and adaptation in a model of adult neurogenesis [PDF]
arXiv, 2001 Adult neurogenesis has long been documented in the vertebrate brain, and recently even in humans. Although it has been conjectured for many years that its functional role is related to the renewing of memories, no clear mechanism as to how this can be achieved has been proposed.
arxiv
Systemic Problems: A perspective on stem cell aging and rejuvenation. [PDF]
, 2015 This review provides balanced analysis of the advances in systemic regulation of young and old tissue stem cells and suggests strategies for accelerating development of therapies to broadly combat age-related tissue degenerative pathologies.
CONBOY, Irina M +2 more
core +2 more sources
Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering
Aggregate, EarlyView.Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang +3 more
wiley +1 more source
Systematic review on spheroids from adipose‐derived stem cells: Spontaneous or artefact state?
Journal of Cellular Physiology, Volume 237, Issue 12, Page 4397-4411, December 2022., 2022 Our proposed model of spheroid isolation from liposuction fat. The tissue disintegration releases the pre‐existing spheroids as intact structures. This could be the ideal technique to culture cells in suspension because it avoids a preliminary adhesion isolation step and thus an upstream cell selection.
Anna Barbara Di Stefano +5 more
wiley +1 more source
Neural Plasticity, 2014 Glucagon-like peptide-1 (GLP-1) regulates carbohydrate metabolism and promotes neurogenesis. We reported an inverse correlation between adult body mass and neurogenesis in nonhuman primates.
Jeremy D. Coplan +6 more
doaj +1 more source
Multifunctional Ultra‐Bright Plasmonic Gold@Fluorescence Nanoprobe for Biomedical Applications
Aggregate, EarlyView.Plasmonic gold nanoparticles (AuNPs) with intrinsic superiorities in metal‐enhanced fluorescence (MEF) have been widely utilized in amplifying signal enhancement, fluorescent labeling, and theranostics. This review systematically discusses plasmonic AuNPs‐driven MEFs, from their enhancement mechanisms, influencing factors, and enhanced types, to their ...
Caiping Ding +4 more
wiley +1 more source
Journal of Cellular Physiology, Volume 237, Issue 12, Page 4563-4579, December 2022., 2022 Abstract The loss of NPC1 or NPC2 function results in cholesterol and sphingolipid dyshomeostasis that impairs developmental trajectories, predisposing the postnatal brain to the appearance of pathological signs, including progressive and stereotyped Purkinje cell loss and microgliosis.
Alessandro Rava +8 more
wiley +1 more source
Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus [PDF]
, 2000 Luciene Covolan +3 more
+4 more sources
On the role of neurogenesis in overcoming catastrophic forgetting [PDF]
arXiv, 2018 Lifelong learning capabilities are crucial for artificial autonomous agents operating on real-world data, which is typically non-stationary and temporally correlated. In this work, we demonstrate that dynamically grown networks outperform static networks in incremental learning scenarios, even when bounded by the same amount of memory in both cases ...
arxiv
The peritumoral brain zone in glioblastoma: where we are and where we are going
Journal of Neuroscience Research, Volume 101, Issue 2, Page 199-216, February 2023., 2023 Abstract Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current therapies are not curative, and patients' outcomes remain poor with an overall survival of 20.9 months after surgery. The typical growing pattern of GBM develops by infiltrating the surrounding apparent normal brain tissue within which the recurrence is ...
Martina Giambra +8 more
wiley +1 more source