Results 151 to 160 of about 174,681 (296)

Extracellular matrix remodeling upregulates hippocampal neurogenic niche stiffness and impairs neurogenesis in Alzheimer's disease. [PDF]

Alzheimers Dement
Sun W, Yang B, Zheng H, Wang Q, Shi Y, Wang G, Yin W, Wang H, Qi X, Yao Y, Wang J, Cui S, Cui K, Mao J, Xia Y, Deng J, Zhao S, Wang Z, Liu F, Yi M, Ding J, Le W, Li X, Yuan J, Wan Y, Zheng J.   +25 more
europepmc   +1 more source

GoncalvesLab/Frechou-et-al-Neurogenesis: Analysis code for Frechou et al. publication

<p>Code used to analyze calcium imaging data in Frechou et al. publication "Adult neurogenesis improves spatial information encoding in the mouse hippocampus"</p ...
Maria Agustina Frechou
core   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

High-intensity interval exercise affects neurogenesis and angiogenesis differently in diabetic and non-diabetic mice. [PDF]

Front Neurosci
Mjønes HS, Havik M, Seferi G, Morland C.   +3 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Potential Role of Sphingosine-1-Phosphate and Its Receptors in the Reparative Processes of the Adult Brain. [PDF]

Int J Mol Sci
Gutner UA, Shupik MA, Alessenko A.
europepmc   +1 more source

Impaired spatio-temporal coordination of subventricular neurogenesis is restored by physical exercise

, 2015
A major aim of neural stem cells field is to harness endogenous neurogenesis to replace neurons damaged as a consequence of brain damage and neurodegeneration.
SARAULLI, DANIELE, Scopa, Chiara, SCARDIGLI, Raffaella, Farioli Vecchioli, Stefano, Costanzi, Marco, MASTRORILLI, VALENTINA, CESTARI, VINCENZO, Tirone, Felice   +7 more
core  

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

The hippocampal subgranular zone neurogenic niche: a modular perspective on neural stem cell regulation. [PDF]

Front Cell Neurosci
Zhao T, Zhou Y, Pan P, Jia Y, Zhang X, An Z, Yan J, Li Q, Zhou Y.   +8 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source