Results 131 to 140 of about 155,428 (262)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

From the Scientific Underground to the Height of Recognition: The 40th Anniversary of Rita Levi-Montalcini's Nobel Prize and the Promising Horizon in Psychiatry. [PDF]

Neurochem Res
Junkes L, Nardi AE, Clementi E.
europepmc   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

The Dentate Gyrus Grows Throughout Life Despite Turnover of Developmentally-Born Neurons. [PDF]

Hippocampus
Ciric T, Cahill SP, Lin T, Choi SA, Snyder JS.   +4 more
europepmc   +1 more source

Hyperbaric oxygen therapy improves neurogenesis and brain blood supply in piriform cortex in rats with vascular dementia

, 2010
Background: Neural stem cell treatment and neurogenesis stimulation have gained attention as potential treatments for vascular dementia (VD). Currently, research mainly focuses on neurogenesis occurring in the sub-ventricular zone and dentate gyrus ...
Wang, Shu-Nan, Wang, Jing-Zhou, Yang, Qin-Wu, Wang, Qiang, Wang, Yong, Luo, Yue-Jiao, Zhang, Tao   +6 more
core  

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Progenitor diversity during formation of the mammalian neocortex. [PDF]

Front Neurosci
Atak Z, Haydar TF.
europepmc   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Goras Georgios, Thrasyvoulou Andreas, Tsilimpokou Evanthia   +2 more
wiley   +1 more source

Caffeic acid restores neurogenesis and synaptic integrity under glucolipotoxic stress by suppressing inflammation and pyroptosis. [PDF]

Metab Brain Dis
Tsai IN, Xie XN, Ko PE, Tsai YC, Chen CC, Hsu LS, Wang CJ.   +6 more
europepmc   +1 more source