Results 161 to 170 of about 155,428 (262)

Deciphering the microenvironment of adult neurogenesis: a perspective from neurodegenerative diseases. [PDF]

Transl Neurodegener
Lao ZK, Xu NJ.
europepmc   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Adult neurogenesis: New neurons, new opportunities. [PDF]

Cell Stem Cell
Doludda B, Barde W, D'Egidio F, Fitzsimons CP, Frisén J, Gage FH, Jessberger S, Lazarov O, Lie DC, Lucassen PJ, de Lucia C, Salta E, Song H, Song J, Thuret S, Toda T, Kempermann G.   +16 more
europepmc   +1 more source

Exploring Interactive Effects of Arsenic and Selenium Exposure on Larval Zebrafish (Danio rerio)

Environmental Toxicology, EarlyView.
ABSTRACT Arsenic contamination in aquatic ecosystems is a major environmental concern. Selenium (Se) helps mitigate oxidative stress and hence could reduce the toxic effects of arsenic. However, Se can also be toxic at high concentrations. Given that these metalloids commonly co‐occur in the environment, there is a pressing need for further research ...
Owen Luo, Jinnath Rehana Ritu, Md Helal Uddin, Sravan Kumar Putnala, Mahesh Rachamalla, Som Niyogi, Douglas P. Chivers   +6 more
wiley   +1 more source

Decreased hippocampal neurogenesis and post-stroke depression. [PDF]

Front Psychiatry
Tang X, Ran L, Li W.
europepmc   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

Beyond Hormone Levels: Thyroid Hormone Signaling from Neurogenesis to Alzheimer's Disease. [PDF]

Cells
Del Seppia C, Sabatino L.
europepmc   +1 more source

Environmentally Realistic Metal Mixture Concentration Impacts Early Development in Zebrafish Larvae

Environmental Toxicology, EarlyView.
ABSTRACT The dispersion of metals in the environment leads to the presence of metal mixtures in impacted ecosystems, but few studies have addressed their impact on early developmental processes in fish. Here, we investigated the effect of metal mixtures reported in the Doce River basin in Brazil, including Fe, Mn, and Cd, either singly or as a mixture ...
Anderson K. S. Macêdo, Willian A. Thompson, Hélio B. Santos, Ralph G. Thomé, Mathilakath M. Vijayan   +4 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source