Results 221 to 230 of about 218,517 (358)

Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions

Ibrain, EarlyView.
Alzheimer's disease treatment is evolving rapidly, with emerging strategies targeting multiple disease pathways. This graphical abstract highlights the shift from traditional therapies to innovative approaches that hold promise for improving outcomes.
Tapas Kumar Mohapatra, Reena Rani Nayak, Ankit Ganeshpurkar, Prashant Tiwari, Dileep Kumar   +4 more
wiley   +1 more source

The fate of interneurons, GABAA receptor sub‐types and perineuronal nets in Alzheimer's disease

Brain Pathology, Volume 33, Issue 1, January 2023., 2023
Abstract Alzheimer's disease (AD) is the most common neurological disease, which is associated with gradual memory loss and correlated with synaptic hyperactivity and abnormal oscillatory rhythmic brain activity that precedes phenotypic alterations and is partly responsible for the spread of the disease pathology.
Afia B. Ali, Anam Islam, Andrew Constanti   +2 more
wiley   +1 more source

Therapeutic modulation of neurogenesis to improve hippocampal plasticity and cognition in aging and Alzheimer's disease. [PDF]

Neurotherapeutics
Mostafa M, Disouky A, Lazarov O.
europepmc   +1 more source

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

Interdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu, Zhendong Huang, Xiner Tan, Wei Du, Ziyang Wang, Xinru Zhou, Hao Pan, Lili Chen, Yiyuan Kang, Longquan Shao   +9 more
wiley   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

British Journal of Pharmacology, EarlyView., 2023
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi, Caroline Gora, Ana Dudas, Xavier Leray, Véronique Bozon, Pascale Crépieux, Lucie P. Pellissier   +6 more
wiley   +1 more source

Effects of Testosterone and Its Major Metabolites upon Different Stages of Neuron Survival in the Dentate Gyrus of Male Rats. [PDF]

Biomolecules
Spritzer MD, Roy EA, Calhoun KMK, Schneider-Lynch ZE, Panella L, Michaelcheck C, Qian A, Kelly ED, Barr H, Hall E, Cunningham B, Nguyen HHM, Xu D, Barker JM, Galea LAM.   +14 more
europepmc   +1 more source

The Role of tRNA Fragments on Neurogenesis Alteration by H₂O₂-induced Oxidative Stress. [PDF]

J Mol Neurosci
Karacicek B, Katkat E, Binokay L, Ozhan G, Karakülah G, Genc S.   +5 more
europepmc   +1 more source

Granule Cell Neurogenesis After Status Epilepticus in the Immature Rat Brain [PDF]

, 2000
Raman Sankar, Don Shin, Hantao Liu, Hiroshi Katsumori, Claude G. Wasterlain   +4 more
openalex   +1 more source

Neurogenesis drives hippocampal formation-wide spatial transcription alterations in health and Alzheimer's disease. [PDF]

Front Dement
Morrissey ZD, Kumar P, Phan TX, Maienschein-Cline M, Leow A, Lazarov O.   +5 more
europepmc   +1 more source

Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus

, 2000
Valérie Lemaire, Muriel Koehl, Michel Le Moal, Djoher Nora Abrous   +3 more
openalex   +1 more source