Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/<i>SIRT1</i> Axis. [PDF]
Xu T +17 more
europepmc +1 more source
Comparative analysis of microRNAs in bovine colostrum and neonatal calf blood
Abstract BACKGROUND MicroRNAs (miRNAs) are short non‐coding RNAs that participate in a wide range of biological processes. MiRNAs are present in high concentrations in colostrum, and these may be potentially transferred to newborn calves being fed colostrum.
Do T Hue +7 more
wiley +1 more source
Loss of function variants in HPDL impair human cortical development via alterations of mitochondrial function. [PDF]
Baggiani M +11 more
europepmc +1 more source
Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis
This study investigated perioperative changes in olfactory bulb volume (OBV) in patients with eosinophilic chronic rhinosinusitis using high‐resolution 3T MRI. Postoperative increases in OBV were associated with improvements in olfactory identification, suggesting a potential link between olfactory bulb structural plasticity and functional recovery ...
Keisuke Yamamoto +8 more
wiley +1 more source
LRP1 in Adult-Born Neural Stem Cells Modulates Neurogenesis and Hippocampal Memory. [PDF]
Dietert K +5 more
europepmc +1 more source
Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra +5 more
wiley +1 more source
High dopamine impairs early neuronal identity and morphology in human hippocampal progenitor cells. [PDF]
Ravji M, Mandal G, Batzu L, Thuret S.
europepmc +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Sex differences in neurobehavior and the adult hippocampal neurogenic niche: influence of traumatic brain injury and CLIP antagonism. [PDF]
Iannucci J +9 more
europepmc +1 more source
In Vivo Mapping of Catecholaminergic Loss and Iron Deposition in Huntington's Disease
Abstract Background The pathophysiology of Huntington's disease (HD) remains obscure. Magnetic resonance imaging (MRI) can reveal in vivo molecular changes related to disease pathology. Objectives To investigate catecholaminergic neuronal integrity and subcortical brain iron accumulation in HD employing neuromelanin‐sensitive MRI, and quantitative ...
Edoardo R. de Natale +11 more
wiley +1 more source

