Results 221 to 230 of about 177,971 (301)

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Tanycyte BMAL1 regulates high-fat diet weight gain and shapes arcuate neurogenesis in female mice. [PDF]

Cell Rep
Iascone DM, Pivarshev P, Yang J, Valencia ML, Noya SB, Lin H, Holman CD, Anafi RC, Bedont JL, Sehgal A.   +9 more
europepmc   +1 more source

Patient iPSC‐derived astrocytes reveal impaired homeostasis and reactive‐like features in propionic acidemia

The Journal of Pathology, EarlyView.
Abstract Propionic acidemia (PA) is a neurometabolic disorder caused by propionyl‐CoA carboxylase deficiency with frequent neurological involvement, yet cell‐type‐specific mechanisms remain poorly defined. We established human induced pluripotent stem cell (iPSC)‐derived astrocytes (iAs) from patients harboring PCCA or PCCB mutations and investigated ...
Irene González‐Garnacho, Mar Álvarez, Francisco Zafra, Pilar Rodríguez‐Pombo, Lourdes R Desviat, Eva Richard   +5 more
wiley   +1 more source

Quiescence as an Active and Dynamic Regulator of Neural Stem Cells in Adult Olfactory Neurogenesis. [PDF]

Eur J Neurosci
Morante-Redolat JM, Fariñas I.
europepmc   +1 more source

Quantitative MRI Assessment of Gyrification and Brain Volume in Congenital Cytomegalovirus Fetuses and Postnatal Outcome

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Quantitative assessment of the impact of cytomegalovirus (CMV) infection on fetal brain development beyond conventional imaging remains limited. We aimed to quantify cortical gyrification and brain volumes in CMV‐exposed fetuses, compare groups with varying severities of conventional MRI findings, and evaluate postnatal outcomes ...
Or R. Sadan, Bossmat Yehuda, Maya Yanko, Aaron Olender, Yair Wexler, Galia Grisaru‐Soen, Yael Leitner, Aviad Rabinowich, Bella Specktor‐Fadida, Dana Schonberger, Shira Ben Haim, Tal Zimels, Leo Joskowicz, Liat Ben Sira, Dafna Ben Bashat   +14 more
wiley   +1 more source

Deiodinase 3 Deficiency Impairs Hippocampal and Lateral Ventricle Neurogenesis in Middle-Aged Female Mice. [PDF]

Int J Mol Sci
Wu Z, Martinez ME, Hernandez A.
europepmc   +1 more source

Rheological and Mechanical Assessment of Injectable Hydrogels: A Framework for Structure–Property Analysis

Polymer Engineering &Science, EarlyView.
A rheological and mechanical assessment framework to construct structure‐property‐application relationships for injectable hydrogels. ABSTRACT Injectable hydrogels have attracted massive research attention thanks to their potential biomedical applications.
Hai Xin, D. S. Abdullah Al Maruf, Boyang Wan   +2 more
wiley   +1 more source

A historical specimen of False Lingzhi (Ganoderma lucidum) resolves a 245‐year‐old confusion within an important medicinal mushroom group

PLANTS, PEOPLE, PLANET, EarlyView.
Traditional Chinese Medicine has expanded far beyond Asia, with growing markets in North America and Europe for supplements and functional foods. Lingzhi or Reishi (Ganoderma lingzhi), a well‐known medicinal mushroom, is valued for its anti‐inflammatory and anticancer properties.
Torda Varga, Spike R. J. Parker, Alessandro Agorini, Alexandra Dombrowski, Lewis Hadfield, A. Martyn Ainsworth, David L. Hawksworth, Masoomeh Ghobad‐Nejhad, Viktor Papp   +8 more
wiley   +1 more source

The Repair Manual of a Fruit Fly Brain. [PDF]

Int J Mol Sci
Peetz I, Blum A, Ahern-Djamali S, Boekhoff-Falk G.   +3 more
europepmc   +1 more source

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

Precision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source