Results 221 to 230 of about 174,681 (296)

Hypoxia inducible factor-1α-driven signaling networks regulating adult neurogenesis via Notch, Wnt, and MAPK pathways. [PDF]

Mol Biol Rep
Cornelio-Martínez S, Lagunas-Rangel FA.
europepmc   +1 more source

Environmentally Realistic Metal Mixture Concentration Impacts Early Development in Zebrafish Larvae

Environmental Toxicology, EarlyView.
ABSTRACT The dispersion of metals in the environment leads to the presence of metal mixtures in impacted ecosystems, but few studies have addressed their impact on early developmental processes in fish. Here, we investigated the effect of metal mixtures reported in the Doce River basin in Brazil, including Fe, Mn, and Cd, either singly or as a mixture ...
Anderson K. S. Macêdo, Willian A. Thompson, Hélio B. Santos, Ralph G. Thomé, Mathilakath M. Vijayan   +4 more
wiley   +1 more source

From chromatin dynamics to brain disease: Polycomb-Trithorax mechanisms in neurodevelopment. [PDF]

Trends Neurosci
Castro VL, So MB, Peng JC.
europepmc   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Corrigendum to 'An advanced chitosan based sponges dressing system with antioxidative, immunoregulation, angiogenesis and neurogenesis for promoting diabetic wound healing' [Mater. Today Bio (2024), 101361]. [PDF]

Mater Today Bio
Fan X, Su Z, Zhang W, Huang H, He C, Wu Z, Zhang P.   +6 more
europepmc   +1 more source

EE2 and the Fish Brain: Age‐Dependent Impact of 17α‐Ethinylestradiol on Brain Cell Proliferation and Behavior in Sea Bass Larvae

Environmental Toxicology, EarlyView.
ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia, Stephanie Olivier, Céline Thomasse, Christophe Minier, Marie‐Pierre Halm‐Lemeille, Christelle Jozet‐Alves, Salima Aroua   +6 more
wiley   +1 more source

Neurodevelopmental outcomes relevant to autism in juvenile mice exposed to PCB 11 in the maternal diet throughout gestation and lactation. [PDF]

Front Toxicol
Wilson RJ, Panesar HK, Dursun I, Mendieta R, Andrew PM, Li X, Lehmler HJ, Lein PJ.   +7 more
europepmc   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Voluntary running exercise is associated with metabolic shifts linked to adult hippocampal neurogenesis. [PDF]

Sci Rep
Vazquez-Medina A, Ruíz-Bolivar D, Morales-Iglesias P, Marín-Hernandez K, Rivera-Ortiz D, Vizcarrondo-Fornaris F, Bello-Rivera B, Sierra-Medina B, Rodríguez-Soto S, Chorna N.   +9 more
europepmc   +1 more source

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

Integrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu, Daoyuan Hu, Min Chen, Xiuguang Mao   +3 more
wiley   +1 more source