Results 301 to 310 of about 218,517 (358)

Self-Produced Brain-Like ECM From 3D-Cultured Dermal Fibroblasts Enhances Neuronal Growth and Survival. [PDF]

Biotechnol J
Roy V, Bienjonetti I, Paquet A, Gros-Louis F.   +3 more
europepmc   +1 more source

Aged Gut Microbiota Contributes to Cognitive Impairment and Hippocampal Synapse Loss in Mice

Aging Cell, EarlyView.
Li et al. revealed that aged gut microbiota induces cognitive decline and microglia‐mediated synapse loss. Fecal Bifidobacterium pseudolongum abundance was reduced in patients with cognitive impairment and microbiota transplantation from patients with fewer B.p abundance yielded worse cognitive behavior in mice.
Mingxiao Li, Yiyang Bao, Jiaoqi Ren, Wenjing Wei, Xuefei Yu, Xiaofang He, Mutalifu gulisima, Lili Sheng, Ningning Zheng, Jianbo Wan, Houguang Zhou, Ling Zhao, Houkai Li   +12 more
wiley   +1 more source

Water extract of <i>Humulus japonicus</i> improves age‑related cognitive decline by inhibiting acetylcholinesterase activity and the acetylcholine signaling pathway. [PDF]

Mol Med Rep
Kim JE, Min KS, Go J, Park HY, Choi YK, Lee IB, Shin J, Cho HJ, Kim HS, Hwang DY, Oh WK, Kim KS, Lee CH.   +12 more
europepmc   +1 more source

Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells

Aging Cell, EarlyView.
Expression of HIRA in embryonic melanoblasts is required for proper epigenetic programing and lineage differentiation. Although HIRA deficiency results in a mild phenotype at birth and young adulthood, the melanocytic lineage is sensitive to proliferative challenge, prone to loss of stem cells and dramatically accelerated hair greying in later life ...
Farah Jaber‐Hijazi, Rouven Arnold, Karthic Swaminathan, Kathryn Gilroy, Alexander T. Wenzel, Anthony Lagnado, Kristina Kirschner, Neil Robertson, Claire Reid, Neil Fullarton, Jeff Pawlikowski, Taranjit Singh Rai, Ian Baranyk, Christina Huan Shi, Kevin Y. Yip, Karen Blyth, Jill P. Mesirov, Melissa L. Harris, João F. Passos, Laura M. Machesky, Peter D. Adams   +20 more
wiley   +1 more source

Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction. [PDF]

BMC Anesthesiol
Lin J, Zhu X, Li X, Hong Y, Liang Y, Chen S, Feng C, Cao L.   +7 more
europepmc   +1 more source

SGLT2 Inhibition by Enavogliflozin Significantly Reduces Aβ Pathology and Restores Cognitive Function via Upregulation of Microglial AMPK Signaling in 5XFAD Mouse Model of Alzheimer's Disease

Aging Cell, EarlyView.
SGLT2 inhibition with Enavogliflozin significantly improves cognitive function and reduces Aβ pathology in the 5XFAD mouse model of Alzheimer's disease. Through AMPK activation, Enavogliflozin enhances microglial mitochondrial function and Aβ phagocytosis while reducing neuroinflammation.
Jihui Han, Jaehoon Song, Eun Sun Jung, Ji Won Choi, Hye Young Ji, Inhee Mook‐Jung   +5 more
wiley   +1 more source

Functional cobalt-doped hydrogel scaffold enhances concurrent vascularization and neurogenesis. [PDF]

J Nanobiotechnology
Liu J, Kang J, Zou T, Hu M, Zhang Y, Lin S, Liang Y, Zhong J, Zhao Y, Wei X, Zhang C.   +10 more
europepmc   +1 more source

Linking Adult Olfactory Neurogenesis to Social Reproductive Stimuli: Mechanisms and Functions. [PDF]

Int J Mol Sci
Bovetti S, Bonzano S, Luzzati F, Dati C, De Marchis S, Peretto P.   +5 more
europepmc   +1 more source

The Secreted Glycoprotein Noelin-1 Promotes Neurogenesis in Xenopus

, 2001
Tanya A. Moreno, Marianne Bronner‐Fraser   +1 more
openalex   +1 more source

A Comprehensive Overview of Stress, Resilience, and Neuroplasticity Mechanisms. [PDF]

Int J Mol Sci
Buenrostro-Jáuregui MH, Muñóz-Sánchez S, Rojas-Hernández J, Alonso-Orozco AI, Vega-Flores G, Tapia-de-Jesús A, Leal-Galicia P.   +6 more
europepmc   +1 more source