Neurogenic orthostatic hypotension after treatment with sorafenib. [PDF]
A man in his 70s with a history of fatigue, abdominal pain, and a palpable abdominal mass was found to have a peritoneal desmoid tumour. One year after diagnosis, he was prescribed sorafenib to limit tumour growth. Two months later, he developed dyspnoea on exertion and lower extremity weakness and was reported to have supine hypertension and ...
Wegner Wippel C +3 more
europepmc +6 more sources
Unraveling the stride: exploring the influence of neurogenic orthostatic hypotension on gait and balance in Parkinson's disease. [PDF]
Neurogenic orthostatic hypotension (nOH) and gait impairment are frequent sources of disability in Parkinson’s disease (PD). However, the impact of nOH on balance and gait features remains unclear. This cross-sectional study aimed to assess the influence
Imbalzano G +8 more
europepmc +4 more sources
Neurogenic Orthostatic Hypotension. Lessons From Synucleinopathies. [PDF]
Abstract Maintenance of upright blood pressure critically depends on the autonomic nervous system and its failure leads to neurogenic orthostatic hypotension (NOH). The most severe cases are seen in neurodegenerative disorders caused by abnormal α-synuclein deposits: multiple system atrophy (MSA), Parkinson’s disease, Lewy body dementia,
Idiaquez JF +3 more
europepmc +6 more sources
Current Landscape of Compression Products for Treatment of Postural Orthostatic Tachycardia Syndrome and Neurogenic Orthostatic Hypotension. [PDF]
Background/Objectives: Patients with postural orthostatic tachycardia syndrome (POTS) or neurogenic orthostatic hypotension (nOH) experience vertigo, confusion, and syncope.
Mitra K +6 more
europepmc +4 more sources
Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension [PDF]
Objective The efficacy and safety of 1‐month atomoxetine and midodrine therapies were compared. Three‐month atomoxetine and combination therapies were investigated for additional benefits.
Jung‐Ick Byun +13 more
doaj +5 more sources
Neurogenic Orthostatic Hypotension: a Common Complication of Successful Pancreas Transplantation [PDF]
Background. Orthostatic hypotension (OH) is a poorly understood complication of simultaneous pancreas–kidney (SPK) transplantation. We sought to determine the incidence, timing, and relationship of OH to rapid glycemic control in the early posttransplant
Samantha A. Kuten, PharmD +9 more
doaj +3 more sources
Genetics of Neurogenic Orthostatic Hypotension in Parkinson’s Disease, Results from a Cross-Sectional In Silico Study [PDF]
The genetic basis of Neurogenic Orthostatic Hypotension (NOH) in Parkinson’s disease (PD) has been inadequately explored. In a cross-sectional study, we examined the association between NOH and PD-related single-nucleotide polymorphisms (SNPs) and mapped
Guenson Chevalier +7 more
doaj +3 more sources
Droxidopa Persistence in Neurogenic Orthostatic Hypotension May Be Affected by Titration Approach [PDF]
Fahd Amjad,1 Brett Polenchar,2 Antonella Favit3 1Department of Neurology, Georgetown University Hospital Pasquerilla Healthcare Center, Washington, DC, USA; 2Business Insights, Lundbeck, Deerfield, IL, USA; 3Medical Affairs, Lundbeck, Deerfield, IL ...
Amjad F, Polenchar B, Favit A
doaj +4 more sources
Early-onset hereditary isolated non-neurogenic orthostatic hypotension in a Swedish family. [PDF]
Purpose Orthostatic hypotension is a common condition with heterogeneous and, in many cases, unclear underlying pathophysiology. Frequent symptoms are syncope and falls with a strong impact on daily life.
Fagius J, Klar J, Dahl N.
europepmc +4 more sources
Characterization of the changes in supine blood pressure with long‐term use of droxidopa in patients with neurogenic orthostatic hypotension [PDF]
Background and Aims Patients with neurogenic orthostatic hypotension (nOH) due to autonomic dysfunction may also experience supine hypertension (defined as supine systolic blood pressure [SBP] ≥140 mmHg).
L. Arthur Hewitt +5 more
doaj +4 more sources

