A Scoping Review of the Oral Treatment Options for the Management of Detrusor Sphincter Dyssynergia
ABSTRACT Background Adult neurogenic lower urinary tract dysfunction may be associated with detrusor sphincter dyssynergia (DSD). Given the sparsity of the literature and the absence of official guidelines regarding the use of oral medications in the management of DSD, this scoping review aims to critically assess the available evidence to guide future
Angélique Tousignant+4 more
wiley +1 more source
Pharmacokinetics and pharmacodynamics of ampreloxetine, a novel, selective norepinephrine reuptake inhibitor, in symptomatic neurogenic orthostatic hypotension [PDF]
Arthur Lo+4 more
openalex +1 more source
Clinical presentation and long-term follow-up of dopamine beta hydroxylase deficiency [PDF]
Dopamine beta hydroxylase (DBH) deficiency is an extremely rare autosomal recessive disorder with severe orthostatic hypotension, that can be treated with L-threo-3,4-dihydroxyphenylserine (L-DOPS).
Deinum, Jaap+13 more
core +2 more sources
ABSTRACT Background Urinary and sexual symptoms are common following neurological disease, and we aimed to develop multidisciplinary inter‐society evidence‐based management guidelines. Methods The ADAPTE framework was used, and a systematic search of guidelines published in different languages was performed.
Jalesh N. Panicker+35 more
wiley +1 more source
Reduced brainstem functional connectivity in patients with peripheral autonomic failure
Autonomic homeostasis is dependent upon several brainstem nuclei, as well as several cortical and subcortical structures. Together, these sites make up, in part, the central autonomic network.
Jacquie Baker, Kurt Kimpinski
doaj
Frequency of orthostatic hypotension in the Pooled Resource Open-Access ALS Clinical Trials database
PurposeTo explore the frequency of orthostatic hypotension (OH) in a large sample of amyotrophic lateral sclerosis patients (ALS).MethodsFrom the PRO-ACT database, data of 1,240 ALS patients were analyzed, focusing on blood pressure and heart rate before
C. Quarracino+6 more
doaj +1 more source
Effective management of neurogenic orthostatic hypotension and supine hypertension (SH-OH) due autonomic failure requires a frequent and timely adjustment of medication throughout the day to maintain the blood pressure (BP) within the normal range, i.e.,
Isaac S. Chang+4 more
doaj +1 more source
ODP291 A Series of COVID Reinfections in a Vaccinated Patient leading to Development of Neurogenic Orthostatic Hypotension and Postural Orthostatic Tachycardia [PDF]
Clio Musurakis+2 more
openalex +1 more source
The Many Faces of REM Sleep Behavior Disorder. Providing Evidence for a New Lexicon
ABSTRACT Background People with idiopathic/isolated REM sleep behavior disorder (iRBD) are highly heterogeneous, showing mild motor, cognitive, and dysautonomia symptoms. The aim of this study is to unveil the clinical heterogeneity of iRBD with a specific reference to overlapping features with prodromal Parkinson's disease (pPD) and prodromal dementia
Dario Arnaldi+18 more
wiley +1 more source
Neurogenic orthostatic hypotension – management update and role of droxidopa
Joy Vijayan,1 Vijay K Sharma1,21Department of Medicine, Division of Neurology, National University Health System, 2Yong Loo Lin School of Medicine, National University of Singapore, SingaporeAbstract: Orthostatic hypotension (OH) is defined as a ...
Vijayan J, Sharma VK
doaj