Results 71 to 80 of about 4,737 (214)

Decreased Noradrenaline (Norepinephrine) Synthesis in Neurogenic Orthostatic Hypotension [PDF]

Circulation, 1968
Three patients with idiopathic orthostatic (postural) hypotension were infused over a 4-hr period with 104.6 µc of 3-hydroxytyramine-2- 14 C, the immediate precursor in the synthesis of the sympathetic neurohormone, that is, noradrenaline (norepinephrine).
M C, Goodall, W R, Harlan, H, Alton
openaire   +2 more sources

Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction

Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Inhibition of vasocontraction accounts for side effects in treating voiding symptoms in benign prostatic hyperplasia (BPH). We examined the vasoactivity of compounds previously showing inhibition of prostate smooth muscle contraction. Contractions of porcine renal interlobar and coronary arteries were induced by agonists or electric field ...
Guangyang Liu, Sheng Hu, Alexander Tamalunas, Oluwafemi Kale, Yajie Xu, Christian G. Stief, Martin Hennenberg   +6 more
wiley   +1 more source

Surgical Neurostimulation for Spinal Cord Injury. [PDF]

, 2017
Traumatic spinal cord injury (SCI) is a devastating neurological condition characterized by a constellation of symptoms including paralysis, paraesthesia, pain, cardiovascular, bladder, bowel and sexual dysfunction.
Cook, Gao, Halim, Heath, Hou, Karlsson, Krueger, Mohammadi, Partida, Pereira, Saitoh, Singh, Werndle   +12 more
core   +2 more sources

Droxidopa in Patients with Neurogenic Orthostatic Hypotension Associated with Parkinson's Disease (NOH306A)

Journal of Parkinson’s Disease, 2014
Background: Neurogenic orthostatic hypotension (nOH) is common in Parkinson's disease (PD), and represents a failure to generate norepinephrine responses appropriate for postural change.
Robert A. Hauser, L. Arthur Hewitt, Stuart Isaacson   +2 more
doaj   +1 more source

Management of Orthostatic Hypotension in Parkinson’s Disease

Journal of Parkinson’s Disease, 2020
Orthostatic hypotension (OH) is a common non-motor feature of Parkinson’s disease that may cause unexplained falls, syncope, lightheadedness, cognitive impairment, dyspnea, fatigue, blurred vision, shoulder, neck, or low-back pain upon standing.
Alessandra Fanciulli, Fabian Leys, Cristian Falup-Pecurariu, Roland Thijs, Gregor K. Wenning   +4 more
doaj   +1 more source

Use of droxidopa for blood pressure augmentation after acute spinal cord injury: case reports [PDF]

Acute and Critical Care
Hypotension secondary to autonomic dysfunction is a common complication of acute spinal cord injury (SCI) that may worsen neurologic outcomes. Midodrine, an enteral α-1 agonist, is often used to facilitate weaning intravenous (IV) vasopressors, but its ...
Christopher S. Hong, Muhammad K. Effendi, Abdalla A. Ammar, Kent A. Owusu, Mahmoud A. Ammar, Andrew B. Koo, Layton A. Lamsam, Aladine A. Elsamadicy, Gregory A. Kuzmik, Maxwell Laurans, Michael L. DiLuna, Mark L. Landreneau   +11 more
doaj   +1 more source

Cardiorespiratory Response to Exercise in Parkinson's Disease: Associations with Autonomic Dysfunction and Physical Activity

Movement Disorders Clinical Practice, Volume 12, Issue 11, Page 1882-1890, November 2025.
Abstract Background Both autonomic dysfunction and low levels of physical activity could contribute to reduced cardiorespiratory fitness in people with Parkinson's disease (PD). However, the interrelationship between these concepts is not well understood.
Kars I. Veldkamp, Sabine Schootemeijer, Hilde Joosten, Bastiaan R. Bloem, Luc J.W. Evers, Nienke M. de Vries   +5 more
wiley   +1 more source

Research status of neurogenic supine hypertension

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Neurogenic supine hypertensive (NSH) is one of the types of autonomic nervous function failure, often occurs in neurogenic orthostatic hypotension (NOH) patients.
Yan DING, Yuan YUAN, Ning LI, Shu⁃qin ZHAN   +3 more
doaj  

Polyneuropathy in Wild‐Type Transthyretin Amyloidosis

European Journal of Neurology, Volume 32, Issue 11, November 2025.
ABSTRACT Introduction Transthyretin amyloidosis (ATTR) is a systemic disorder characterized by the extracellular accumulation of amyloid fibrils, classified as either mutant (ATTRv, v for variant) or wild‐type (ATTRwt), based on the genetic sequence of the transthyretin (TTR) protein.
Maria Ausilia Sciarrone, Francesca Vitali, Valeria Guglielmino, Angela Romano, Giovanni Siconolfi, Marco Ceccanti, Maurizio Inghilleri, Cristina Chimenti, Francesca Graziani, Rosa Lillo, Laura Libonati, Chiara Cambieri, Federica Moret, Vito Stifano, Marco Luigetti   +14 more
wiley   +1 more source

Neurogenic orthostatic hypotension in Parkinson's disease: evaluation, management, and emerging role of droxidopa

Vascular Health and Risk Management, 2014
Stuart H Isaacson, Julia Skettini Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, FL, USA Abstract: Neurogenic orthostatic hypotension (nOH) is due to failure of the autonomic nervous system to regulate blood pressure in
Isaacson SH, Skettini J
doaj