Results 61 to 70 of about 76,921 (190)

Is Droxidopa Safe and Effective in Reducing Symptoms of Neurogenic Orthostatic Hypotension? [PDF]

, 2017
Objective: The objective of this selective EBM review is to determine whether or not droxidopa is safe and effective in reducing the symptoms of neurogenic orthostatic hypotension.
Longo, Nicholas W
core   +1 more source

Blunted tachycardia and cardiac sympathetic denervation in isolated rapid eye movement sleep behavior disorder

BMC Neurology
Background Isolated rapid eye movement sleep behavior disorder (iRBD) serves as a prodromal phase of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB).
Shota Saeda, Yukiyoshi Sumi, Koichi Fujiwara, Hiroshi Kadotani   +3 more
doaj   +1 more source

Neural Correlates of Apathy in Multiple System Atrophy: A Clinical and Perfusion Imaging Study

European Journal of Neurology, Volume 33, Issue 10, October 2026.
In 76 patients with multiple system atrophy (MSA) and relatively preserved global cognition, apathy was present in 55.3%, with no association with motor severity or depressive symptoms. Reduced medial prefrontal cortex (mPFC) perfusion was independently associated with apathy after adjustment for clinical variables, while exploratory covariance ...
Yuki Nakagawa, Atsuhiko Sugiyama, Yoshikazu Nakano, Hajime Yokota, Shigeki Hirano, Masahiro Namiki, Tatsuya Yamamoto, Yoshitaka Yamanaka, Shoichi Ito, Masahiro Mori   +9 more
wiley   +1 more source

Epidemiology, Diagnosis, and Management of Neurogenic Orthostatic Hypotension

Movement Disorders Clinical Practice, 2017
AbstractBackgroundOrthostatic hypotension (OH) is a sustained fall in blood pressure on standing that can cause symptoms of organ hypoperfusion. OH is associated with increased morbidity and mortality and leads to a significant number of hospital admissions, particularly in the elderly (233 per 100,000 patients >75 years of age in the United States).
Jose‐Alberto Palma, Horacio Kaufmann
openaire   +3 more sources

Orthostatic Hypotension, Hypertension Treatment, and Cardiovascular Disease [PDF]

, 2023
IMPORTANCE: There are ongoing concerns about the benefits of intensive vs standard blood pressure (BP) treatment among adults with orthostatic hypotension or standing hypotension.
Rury R. Holman, Cushman, William C, Nigel S. Beckett, Addison A. Taylor, Juraschek, Stephen P, Greg Grandits, Lutgarde Thijs, Thijs, Lutgarde, Wright, Jackson T, Jan A. Staessen, Beckett, Nigel S, William C. Cushman, Barry R. Davis, Anthony M. Ishak, Appel, Lawrence J, Mita, Carol, Edgar R. Miller, Jackson T. Wright, Jiun-Ruey Hu, Lewis A. Lipsitz, Kenneth J. Mukamal, Jennifer L. Cluett, Peters, Ruth, Holman, Rury R, Stephen P. Juraschek, Carol Mita, Ishak, Anthony M, Cluett, Jennifer L, Lipsitz, Lewis A, Ruth Peters, Ruth L. Coleman, Hu, Jiun-Ruey, Staessen, Jan A, Coleman, Ruth L, Davis, Barry R, Mukamal, Kenneth J, Lawrence J. Appel, Grandits, Greg, Miller, Edgar R, Taylor, Addison A   +39 more
core   +1 more source

Neurogenic Orthostatic Hypotension: An Underrecognized Complication of Parkinson Disease

, 2020
BACKGROUND: Neurogenic orthostatic hypotension (nOH) is a common source of disability but is an often untreated nonmotor symptom of Parkinson disease. The key manifestations of nOH include lightheadedness, dizziness, weakness, and fatigue when standing ...
Khemani, Pravin, Mo-Kyung Sin, Sin, Mo-Kyung, Pravin Khemani   +3 more
core   +2 more sources

Neurogenic orthostatic hypotension and supine hypertension in Parkinson\u27s disease and related synucleinopathies: prioritisation of treatment targets

, 2016
Neurogenic orthostatic hypotension and supine hypertension are common manifestations of cardiovascular dysautonomia in Parkinson\u27s disease and related synucleinopathies.
Espay, Alberto J, Lang, Anthony E, Masellis, Mario, LeWitt, Peter A, Hauser, Robert A, Merola, Aristide   +5 more
core   +1 more source

Cancer‐related pain: A bidirectional modulator of cancer progression

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He, Yu Zhang, Qian Liu, Biao Yan, Peiwei Chai, Renbing Jia   +5 more
wiley   +1 more source

High prevalence of orthostatic hypotension in mild dementia [PDF]

, 2009
Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia.
Aarsland, Dag, Nilsen, Dennis W., Tysnes, Ole B, Tysnes, Ole B., Nilsen, Dennis W. T., Rongve, Arvid, Sønnesyn, Hogne, Nore, Sabine, Ballard, Clive, Sonnesyn, Hogne, Nilsen, Dennis W, Aarsland, Dag; id_orcid, Tysnes, Ole-Bjørn   +12 more
core   +1 more source

When Glycaemic Control Comes Too Fast: Treatment‐Induced Neuropathy of Diabetes and Charcot Neuro‐Osteoarthropathy as Emerging Iatrogenic Complications of Rapid Metabolic Correction

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Purpose of Review Diabetes therapeutics can lower glycated haemoglobin (HbA1c) by several percentage points within weeks. While long‐term microvascular risk is reduced by improved glycaemia, abrupt metabolic transitions may destabilise tissues adapted to chronic hyperglycemia.
Dured Dardari
wiley   +1 more source