Droxidopa as an effective treatment for refractory neurogenic orthostatic hypotension and reflex bradycardia in amyloid light-chain amyloidosis: a case report [PDF]
Journal of Medical Case Reports, 2020 Background Droxidopa is an oral treatment for the stepwise treatment of neurogenic orthostatic hypotension from autonomic dysfunction. It has been shown to be useful predominantly with neurogenic orthostatic hypotension secondary to Parkinson’s disease ...
Annie H. Ho +4 more
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Norepinephrine reuptake blockade to treat neurogenic orthostatic hypotension. [PDF]
Clin Auton Res, 2021 <jats:title>Abstract</jats:title><jats:p>GNSS satellite and receiving antennas exhibit group delay variations (GDV), which affect code pseudorange measurements. Like antenna phase center variations, which affect phase measurements, they are frequency-dependent and vary with the direction of the transmitted and received signal.
Eisenhofer G, Goldstein DS.
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Intra-neuronal alpha-synuclein deposition is related to cardiac noradrenergic deficiency and olfactory dysfunction in neurogenic orthostatic hypotension [PDF]
Research SquarePurpose: Neurogenic orthostatic hypotension (nOH) results from deficient reflexive delivery of norepinephrine to cardiovascular receptors in response to decreased cardiac venous return.
Risa Isonaka +3 more
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Safety and efficacy of ampreloxetine in symptomatic neurogenic orthostatic hypotension: a phase 2 trial. [PDF]
Clin Auton Res, 2021 In neurogenic orthostatic hypotension, blood pressure falls when upright owing to impaired release of norepinephrine, leading to dizziness. Ampreloxetine, a selective norepinephrine reuptake inhibitor, increases circulating norepinephrine levels.
Kaufmann H +7 more
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Clinical management of neurogenic orthostatic hypotension
Annals of Movement Disorders, 2019 Neurogenic orthostatic hypotension is a common disorder often seen in elderly patients affected with neurodegenerative disorders and peripheral neuropathies.
Malligurki Raghurama Rukmani +3 more
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An Unusual Case of Neurogenic Orthostatic Hypotension Without Parkinsonian Features
Annals of Internal Medicine: Clinical CasesOrthostatic hypotension is a common cause of syncope, especially in the older adult population. While it is a commonly encountered issue as a cause of syncope, neurogenic orthostatic hypotension (nOH) is less common.
Betul Gok Yavuz, Darian Fard, Asma Malik
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Treatment of Orthostatic Hypotension Due to Autonomic Dysfunction (Neurogenic Orthostatic Hypotension) in a Patient with Cardiovascular Disease and Parkinson's Disease [PDF]
Cardiology and Therapy, 2019 Introduction The prevalence of neurogenic orthostatic hypotension (nOH) increases with age and is associated with autonomic failure in neurodegenerative diseases (e.g., Parkinson's disease).
Peter A. McCullough
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Management of neurogenic orthostatic hypotension: an update [PDF]
The Lancet Neurology, 2008 Orthostatic hypotension (OH) is common in elderly people and in patients with disorders such as diabetes and Parkinson's disease. Grading of the severity of OH and its effect on the patient's quality of life are important. The symptoms vary with orthostatic stress, and subtle symptoms such as tiredness and cognitive impairment should be recognised ...
Phillip A. Low, Wolfgang Singer
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The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension [PDF]
Journal of Neurology, 2017 Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson’s disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including amyloid or ...
Christopher H. Gibbons +13 more
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A Call to Action: The Role of Healthcare Providers in Reducing the Burden Associated with Neurogenic Orthostatic Hypotension [PDF]
Neurology and Therapy, 2020 Plain Language Summary This article discusses what neurogenic orthostatic hypotension (nOH) is, its symptoms, and how patients and healthcare providers (HCPs) can work together to manage nOH symptoms. What is nOH?
Jessie S. Gibson +2 more
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