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Annals of the New York Academy of Sciences, 2022 Abstract The evolution of the nervous system progressed through cellular diversification and specialization of functions. Conceptually, the nervous system is composed of electrically excitable neuronal networks connected by chemical synapses and nonexcitable glial cells that provide for homeostasis and defense.
, Amaia M Arranz
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Decoding the role of zebrafish neuroglia in CNS disease modeling
Brain Research Bulletin, 2021 Neuroglia, including microglia and astrocytes, is a critical component of the central nervous system (CNS) that interacts with neurons to modulate brain activity, development, metabolism and signaling pathways. Thus, a better understanding of the role of
Konstantin N Zabegalov +2 more
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Aging is associated with morphologic and functional decline of the brain active milieu and, in particular, of the neuroglia, which compromises homeostatic support and neuroprotection. Astrocytes in aging undergo complex and region specific changes, manifested by morphologic atrophy and widespread functional asthenia.
Alexey, Semyanov, Alexei, Verkhratsky
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Neuroglia in Neurodegenerative Diseases
Advances in Experimental Medicine and Biology, 2019 This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia.
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Neuroglia in ageing and disease
Cell and Tissue Research, 2014 The proper operation of the mammalian brain requires dynamic interactions between neurones and glial cells. Various types of glial cells are susceptible to morpho-functional changes in a variety of brain pathological states, including toxicity ...
, JOSÉ J Rodríguez, Vladimir Parpura
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General pathophysiology of neuroglia
Handbook of Clinical Neurology / Edited By P J Vinken and G W BruynNeuroglia in the CNS, represented by astroglia, oligodendroglia, and microglia, are responsible for the homeostatic support and protection of the nervous tissue.
, Elly M Hol, Lot D De Witte
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Neuroglia in the healthy brain
Handbook of Clinical Neurology / Edited By P J Vinken and G W BruynThe nervous tissue is composed of neurons and neuroglia, which by working in a tightly coordinated manner, define the function of the nervous system. Neuroglia, defined as homeostatic and defensive cells of the nervous system, are highly heterogeneous in
, Elly M Hol, Lot D De Witte
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Neuroglia in Psychiatric Disorders
2021In the twentieth century, neuropsychiatric disorders have been perceived solely from a neurone-centric point of view, which considers neurones as the key cellular elements of pathological processes. This dogma has been challenged thanks to the better comprehension of the brain functioning, which, even if far from being complete, has revealed the ...
Scuderi, Caterina +3 more
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Neuroglia in neurodegeneration
Brain Research Reviews, 2010Neuroglial cells are fundamental for control of brain homeostasis and they represent the intrinsic brain defence system. All forms in neuropathology therefore inevitably involve glia. The neurodegenerative diseases disrupt connectivity within brain circuits affecting neuronal-neuronal, neuronal-glial and glial-glial contacts.
Heneka, Michael T. +2 more
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