Results 171 to 180 of about 17,069 (317)
Advanced Science, EarlyView.Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao +11 more
wiley +1 more source
A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel
Advanced Science, EarlyView.An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu +12 more
wiley +1 more source
Advanced Science, EarlyView.This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du +12 more
wiley +1 more source
Condition medium of cerebrospinal fluid and retinoic acid induces the transdifferentiation of human dental pulp stem cells into neuroglia and neural like cells [PDF]
, 2017 Sara Haratizadeh +6 more
openalex +1 more source
Advanced Science, EarlyView.This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman +11 more
wiley +1 more source
Neuroglia: A New Open-Access Journal Publishing All Aspects of Glial Research [PDF]
, 2017 Arthur M. Butt +2 more
openalex +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
Advanced Science, EarlyView.The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao +9 more
wiley +1 more source
Advanced Science, EarlyView.Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff +32 more
wiley +1 more source
Neuroglia and the myelin-bearing cell: a symposium. Pathogenesis of multiple sclerosis.
, 1969 E. J. Field
openalex +1 more source