Results 181 to 190 of about 15,346 (302)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Comprehensive review of the cerebral aqueduct: anatomy, embryology, imaging, genetics, molecular, and pathology. [PDF]

Anat Cell Biol
Dituri G, Komune N, Ottone NE, Vučinić N, Donofrio CA, Badaloni F, Fioravanti A, Iwanaga J, Bui CJ, Lockwood J, Dumont AS, Tubbs RS.   +11 more
europepmc   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Developmental dynamics of catshark cranial neural crest cells provide insights into gnathostome facial evolution. [PDF]

Development
Escamilla-Vega E, Murillo-Rincón AP, Seton LWG, Koch AK, Kyomen S, Fortmann-Grote C, Hammel JU, Moritz T, Kaucká M.   +8 more
europepmc   +1 more source

Neuroglia: A New Open-Access Journal Publishing All Aspects of Glial Research [PDF]

, 2017
Arthur M. Butt, Delia Mihaila, Alexei Verkhratsky   +2 more
openalex   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

When neuroglial tissue wanders: a unique case report of subpleural heterotopia in a triploid foetus and review of the literature. [PDF]

Front Med (Lausanne)
Procházka V, Skopelidou V, Delongová P, Hurník P, Špaček R, Matura D, Pavlíček J, Gřegořová A, Vaculová J, Škarda J.   +9 more
europepmc   +1 more source

Implicaciones del sistema serotoninérgico y la neuroglia en lo mecanismos del estrés: Una breve revisión

, 2020
Ivette González Rivera, Diana Berenice Paz Trejo, Oscar Galicia-Castillo, Hugo Sánchez-Castillo   +3 more
openalex   +2 more sources

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

The functional role of glial cells in the pathologic brain as reviewed by Alois Alzheimer in 1910. [PDF]

Mol Neurodegener
Kettenmann H, Lassmann H, Ugursu B, Xiang X.   +3 more
europepmc   +1 more source