Results 211 to 220 of about 21,722 (324)

Decline and fall of aging astrocytes: the human perspective. [PDF]

Neural Regen Res
Verkhratsky A, Semyanov A.
europepmc   +1 more source

IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

Advanced Science, EarlyView.
This study reveals IFITM2 as a key regulator of endocytosis in radial glial cells (RGCs) during brain development. IFITM2's YXXø motif and phosphoinositide‐binding residues (K82/K87) are essential for endosome formation. IFITM2 deficiency disrupts the embryonic cortical neurogenesis, revealing a conserved mechanism linking endocytic dynamics to neural ...
Yuqing Lv, Wenzheng Zou, Lin Li, Shukui Zhang, Jiaqi Liang, Jiali Pu, Jianwei Jiao   +6 more
wiley   +1 more source

Microglial/macrophage activation in the cerebrospinal fluid of neuromyelitis optica spectrum disorders

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Aim The aims of this pilot study were to investigate the levels of biomarkers of microglial/macrophage activation—YKL‐40, sCD163, and sCD14—in patients with neuromyelitis optica spectrum disorder (NMOSD) and determine the possible associations between these biomarkers and Expanded Disability Status Scale (EDSS) scores.
Jinghong Li, Yan He, Honghao Wang, Jinyu Chen   +3 more
wiley   +1 more source

Fischer's ratio and DNA damage in hypoxemia-induced brain injury in rat model: prophylactic role of quercetin and mexamine supplementation. [PDF]

PLoS One
Kadry MO, Ali H.
europepmc   +1 more source

Evaluation of the serum level of estrogen, progesterone, prolactin, and testosterone in patients with trigeminal neuralgia compared to a healthy population. [PDF]

Clin Exp Dent Res, 2023
Lavaee F, Didar S, Afshari A.
europepmc   +1 more source

Astroglial atrophy in Alzheimer’s disease [PDF]

, 2019
Pivoriunas, Augustas, Rodrigues, Jose Julio, Semyanov, Alexey, Verkhratsky, Alexei, Zorec, Robert   +4 more
core   +1 more source

Rational Design and Organoid‐Based Evaluation of a Cocktail CAR‐γδ T Cell Therapy for Heterogeneous Glioblastoma

Advanced Science, EarlyView.
A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu, Zhongzheng Sun, Yingchao Liu, Jiang Liu, Linpei Guo, Guojing Pei, Ying Jiang, Baowang Miao, Zhen Li, Ping Zhang, Dongqi Tang, Wen Zhang, Chengwei Wang   +12 more
wiley   +1 more source

Modeling ALS with Patient-Derived iPSCs: Recent Advances and Future Potentials. [PDF]

Brain Sci
Dawoody Nejad L, Pioro EP.
europepmc   +1 more source

Peer Review #1 of "Perineuronal satellite neuroglia in the telencephalon of New Caledonian crows and other Passeriformes: evidence of satellite glial cells in the central nervous system of healthy birds? (v0.2)"

, 2013
S Szuchet
openalex   +2 more sources

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source