Results 231 to 240 of about 22,201 (325)

Differential regulation of nerve growth factor and brain-derived neurotrophic factor expression in the peripheral nervous system [PDF]

, 1991
HANS THOENEN, Hofer M., ICHIRO MATSUOKA, Lindholm D., Lindholm D., M. HOFER, MICHAEL MEYER   +6 more
core   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Human-specific insights into candidate genes and boosted discoveries of novel loci illuminate roles of neuroglia in reading disorders. [PDF]

Genes Brain Behav
Wei WH, Ma S, Fu B, Song R, Guo H.
europepmc   +1 more source

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

Advanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang, Jiangang Zhang, Yiran Li, Zihan Zhong, Wenhua Li, Haojun Luo, Yanyong Liu, Liujian Ouyang, Zhuoran Jiang, Yuning Sun, Hang Sun, Lulu Liu, Huayu Yang, Yu Wang, Nan Yang, Wenbin Ma, Yilei Mao   +16 more
wiley   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

NPD1 Relieves Neuropathic Pain and Accelerates the Recovery of Motor Function After Peripheral Nerve Injury. [PDF]

Pain Res Manag
Tian Y, Liu Y, Liu C, Huang S.
europepmc   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Environmental enrichment for neuropathic pain via modulation of neuroinflammation. [PDF]

Front Mol Neurosci
Zhang JD, Zhong ZA, Xing WY.
europepmc   +1 more source

El mallorquín Tomás Blanes Víale, discípulo malogrado de don Santiago Ramón y Cajal [PDF]

, 2003
Nieto Amada, J.L.
core  

A Tailored Artificial Biocatalyst for Bacterial Endophthalmitis Therapy via Enhanced Ferroptosis‐Like Death

Advanced Science, EarlyView.
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun, Yingying Jiang, Shibo Zhang, Zhipeng Ding, Lijun Pu, Xinmei Liu, Jun Yang, Xiangkai Zhuge, Jianjun Dai, Yanmin Ju   +9 more
wiley   +1 more source