Results 241 to 250 of about 15,346 (302)

Anti-toxoplasma effect of <i>Moringa oleifera</i> leaves in a rat model of toxoplasmosis-induced pregnancy. [PDF]

Open Vet J
Nurinasari H, Ekawasti F, Sajidan, Purwanto B, Indarto D, Soetrisno, Syiva'a A, Subekti DT, Prihandani SS.   +8 more
europepmc   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Dose-dependent protective profile of trans-anethole in experimental traumatic brain injury in mice via modulation of apoptotic and inflammatory protein expression, and oxidative stress. [PDF]

Acta Cir Bras
Çevik A, Atlas B, Erdoğan G, Atama MS, Altun B, Yılmaz T.   +5 more
europepmc   +1 more source

Rational Design of π‐Conjugated Polymers for Enantioselective Recognition of Amino Acids

Advanced Electronic Materials, EarlyView.
A family of conducting polymers is proposed for the enantioselective recognition of amino acids. The films are generated by electropolymerization of thiophene trimers containing chiral features, with the advantage that the polymerization can be induced at much lower overpotentials compared to classic thiophene monomers, thus avoiding parasitic ...
Gerardo Salinas, Rana Nakar, Getnet Kassahun, Matthieu Raoux, Jochen Lang, Damien Thuau, Mamatimin Abbas, Eric Cloutet, Alexander Kuhn   +8 more
wiley   +1 more source

Noradrenergic excitation of astrocytes supports cognitive reserve. [PDF]

Neural Regen Res
Zorec R, Verkhratsky A.
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Human-specific insights into candidate genes and boosted discoveries of novel loci illuminate roles of neuroglia in reading disorders. [PDF]

Genes Brain Behav
Wei WH, Ma S, Fu B, Song R, Guo H.
europepmc   +1 more source

Ferulic acid ameliorates bisphenol A (BPA)-induced Alzheimer's disease-like pathology through Akt-ERK crosstalk pathway in male rats. [PDF]

Psychopharmacology (Berl)
Khalifa M, Fayed RH, Ahmed YH, Abdelhameed MF, Essa AF, Khalil HMA.   +5 more
europepmc   +1 more source

Modeling ALS with Patient-Derived iPSCs: Recent Advances and Future Potentials. [PDF]

Brain Sci
Dawoody Nejad L, Pioro EP.
europepmc   +1 more source

Neuroprotective effects of ceftriaxone after severe traumatic brain injury in male rats: a behavioral, biochemical, and histological study. [PDF]

Ann Med Surg (Lond)
Esfahani A, Siahposht-Khachaki A, Talebpour Amiri F, Emami Meybodi T, Gheibi M, Ghadirzadeh E, Biabani M, Taghipour G, Safarbalou A, Farzin D.   +9 more
europepmc   +1 more source