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Epilepsy is a group of neurologic diseases characterized by spontaneous, repetitive disruption to neuronal activity. Neurons have been at the core of epilepsy research efforts, and pharmacotherapies historically have been generated by targeting neuronal mechanisms.
Manolia R, Ghouli, Devin K, Binder
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Manolia R, Ghouli, Devin K, Binder
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Aging is associated with morphologic and functional decline of the brain active milieu and, in particular, of the neuroglia, which compromises homeostatic support and neuroprotection. Astrocytes in aging undergo complex and region specific changes, manifested by morphologic atrophy and widespread functional asthenia.
Alexey, Semyanov, Alexei, Verkhratsky
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Alexey, Semyanov, Alexei, Verkhratsky
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1995
Abstract We have emphasized that two special elements, which are really abstractions derived from many examples, form all neural tissue: the neuron with its various processes and the glial cell. The neuron has already been examined in detail, and we shall soon discuss its major process, the nerve fiber.
S Ramón Y Cajal +3 more
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Abstract We have emphasized that two special elements, which are really abstractions derived from many examples, form all neural tissue: the neuron with its various processes and the glial cell. The neuron has already been examined in detail, and we shall soon discuss its major process, the nerve fiber.
S Ramón Y Cajal +3 more
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Imaging can help us understand the role neuroglia plays in health and during the course of neurologic disorders. In vivo microscopy has had a great impact on our understanding of how neuroglia behaves during health and disease. While initially the technique was hindered by the limited penetration depth in brain tissue, recent advancements lead to ...
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Journal of Experimental Biology, 1981
ABSTRACT It is quite usual to see clear fluid collecting continuously on the surface of the spinal cord of ‘functionally decapitate’ cat preparations which have no functioning choroid plexus. The activity of potassium and calcium ions in interstitial fluid of these decapitate spinal cords is equal to that in spinal cords of cats with ...
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ABSTRACT It is quite usual to see clear fluid collecting continuously on the surface of the spinal cord of ‘functionally decapitate’ cat preparations which have no functioning choroid plexus. The activity of potassium and calcium ions in interstitial fluid of these decapitate spinal cords is equal to that in spinal cords of cats with ...
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Neuroglia in hepatic encephalopathy
Neuroglia contribute to the pathophysiology of hepatic encephalopathy (HE) either beneficially or detrimentally. Pathogenesis of HE is linked to damage triggered by blood-derived toxins, with ammonia being the main causative factor. Neuroglial cells, especially astrocytes and microglia, respond to HE-associated systemic and central signals and undergo ...Magdalena, Zielińska +2 more
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Decoding the role of zebrafish neuroglia in CNS disease modeling
Brain Research Bulletin, 2021Murilo Sander DE ABREU +2 more
exaly
Neuroglia in anxiety disorders
Anxiety disorders are some of the most prevalent in the world and are extraordinarily debilitating to many individuals, costing millions in disability. One of the most disabling is posttraumatic stress disorder (Snijders et al., 2020). Understanding the pathophysiology of these illnesses further and the cell types involved will allow better targeting ...Robin E, Bonomi +2 more
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